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NCT05240352 · ClinicalTrials.gov registry record · NA

Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression

A NA study of Anhedonia, sponsored by The University of Texas Health Science Center, Houston.

Recruiting
Registry status
NA
Development phase
45
Enrollment target
1
Study location

NCT05240352 is a NA study of Anhedonia that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 45 participants, below the 108-participant average among 21 other Anhedonia trials with a reported enrollment target (58% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05240352, a NA study of Anhedonia, is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.

RECRUITING
Registry status
NA
Development phase
45 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to investigate whether transcranial direct-current stimulation (tDCS) will engage reward-related brain circuitry, more specifically the uncinate fasciculus (UF) tract, which connects the orbitofrontal cortex (OFC) and nucleus accumbens (NAcc) regions. Also to evaluate whether the changes in the fractional anisotropy (FA) of the UF tract are associated with changes of clinical symptoms of anhedonia and finally to investigate the moderation role of simulated electric fields (EFs) in an association between FA of the UF and symptoms of anhedonia.

Conditions Studied

Anhedonia

Interventions

  • DEVICE sham tDCS
  • DEVICE active tDCS

Study Locations (1)

Texas

  • The University of Texas Health Science Center at Houston - Houston

Trial Details

FieldValue
Enrollment Target 45 participants
Start Date 2022-10-06
Est. Completion 2026-12-01
Phase NA

Sponsor

The University of Texas Health Science Center, Houston

732 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT05240352

The ClinicalTrials.gov registry entry for NCT05240352 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 45 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 108-participant average among 21 other Anhedonia trials with a reported enrollment target (58% lower). The listed sponsor is The University of Texas Health Science Center, Houston, which has 732 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Anhedonia appearing as the primary indexed condition, and to 2 interventions - of which sham tDCS is the first listed.

NCT05240352 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT05240352 about?

NCT05240352 is a clinical study titled "Developing Brain Imaging Analysis Expertise for Personalizing Transcranial Electric Stimulation in Anhedonia Treatment of Patients With Bipolar Depression". The purpose of this study is to investigate whether transcranial direct-current stimulation (tDCS) will engage reward-related brain circuitry, more specifically the uncinate fasciculus (UF) tract, which connects the orbitofrontal cortex (OFC) and nucleus accumbens (NAcc) regions. Also to evaluate wh...

What is the current status of trial NCT05240352?

This trial is currently recruiting. It is a NA study. The enrollment target is 45 participants. The study started on 2022-10-06. Estimated completion is 2026-12-01.

What conditions does trial NCT05240352 study?

This clinical trial studies the following conditions: Anhedonia.

What interventions are being tested in trial NCT05240352?

The interventions under investigation include: sham tDCS (DEVICE), active tDCS (DEVICE).

Who is sponsoring clinical trial NCT05240352?

This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05240352 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.