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NCT06543446 · ClinicalTrials.gov registry record · NA

Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy

A NA study of Heart Failure With Reduced Ejection Fraction, sponsored by University of Rochester.

Recruiting
Registry status
NA
Development phase
3,290
Enrollment target
15
Study locations

NCT06543446 is a NA study of Heart Failure With Reduced Ejection Fraction that is actively recruiting participants, run by University of Rochester. The registered enrollment target is 3,290 participants, below the 3,844-participant average among 27 other Heart Failure With Reduced Ejection Fraction trials with a reported enrollment target (14% lower). The trial reports 15 study locations across 11 states.

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The verdict

NCT06543446, a NA study of Heart Failure With Reduced Ejection Fraction, is actively recruiting participants, sponsored by University of Rochester.

RECRUITING
Registry status
NA
Development phase
3,290 participants
Enrollment target
15
Study locations

Study Summary

The investigators aim to compare the risk of mortality of Non-implantable carioverter defibrillator (ICD) vs. ICD management in patients with heart failure with reduced ejection fraction (HFrEF).

Conditions Studied

Heart Failure With Reduced Ejection Fraction

Interventions

  • PROCEDURE ICD implantation

Study Locations (15)

New York

  • Northwell Health - New York
  • Nuvance Health Hudson Valley Cardiovascular Practice, PC - Poughkeepsie
  • University of Rochester - Rochester

New Jersey

  • Rutgers - New Brunswick
  • The Valley Hospital - Paramus

Alberta

  • University of Calgary - Calgary
  • University of Alberta - Edmonton

Maine

  • MaineHealth - Portland

Maryland

  • Johns Hopkins University - Baltimore

Massachusetts

  • Tufts Medical Center - Boston

Michigan

  • Corewell Health - Grand Rapids

Minnesota

  • Minneapolis Heart Institute Foundation - Minneapolis

Trial Details

FieldValue
Enrollment Target 3,290 participants
Start Date 2025-03-04
Est. Completion 2031-02-28
Phase NA

Sponsor

University of Rochester

636 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06543446

The ClinicalTrials.gov registry entry for NCT06543446 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 3,290 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 3,844-participant average among 27 other Heart Failure With Reduced Ejection Fraction trials with a reported enrollment target (14% lower). The listed sponsor is University of Rochester, which has 636 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Heart Failure With Reduced Ejection Fraction appearing as the primary indexed condition, and to 1 intervention - of which ICD implantation is the first listed.

NCT06543446 reports 15 study locations spanning 11 distinct geographic areas - top geographies include New York, New Jersey, Alberta.

Frequently Asked Questions

What is clinical trial NCT06543446 about?

NCT06543446 is a clinical study titled "Comparative Effectiveness of Prophylactic ICD Versus Non-ICD Therapy". The investigators aim to compare the risk of mortality of Non-implantable carioverter defibrillator (ICD) vs. ICD management in patients with heart failure with reduced ejection fraction (HFrEF).

What is the current status of trial NCT06543446?

This trial is currently recruiting. It is a NA study. The enrollment target is 3,290 participants. The study started on 2025-03-04. Estimated completion is 2031-02-28.

What conditions does trial NCT06543446 study?

This clinical trial studies the following conditions: Heart Failure With Reduced Ejection Fraction.

What interventions are being tested in trial NCT06543446?

The interventions under investigation include: ICD implantation (PROCEDURE).

Who is sponsoring clinical trial NCT06543446?

This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06543446 being conducted?

This trial has 15 study locations across Maine, Maryland, Massachusetts, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.