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NCT06904365 · ClinicalTrials.gov registry record
Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
A clinical trial of Breast Cancer and Lung Cancer, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- 10
- Enrollment target
- 1
- Study location
NCT06904365: Recruiting study of Breast Cancer and Lung Cancer, sponsored by Washington University School of Medicine.
NCT06904365 is a study of Breast Cancer and Lung Cancer that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 10 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06904365, a study of Breast Cancer and Lung Cancer, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Female patients with early onset (\<50 years old) pelvic malignancies such as uterine and rectal cancers are rising in incidence, which often requires pelvic radiation; many of these patients are premenopausal and at a high risk of premature ovarian failure from radiotherapy. Premature ovarian failure carries significant cardiac, musculoskeletal, sexual, and psychosocial morbidity. Ovarian transposition carries variable success rates, is not readily accessible to the general population, and can still be at risk of clinically significant radiotherapy doses. There is an unmet need for innovative techniques to protect ovarian function.
Primary Outcome
Defined as being able to delineate at least one ovary (if only one is visible, must be the same ovary) for ≥60% of CBCT sessions per patient.
Conditions Studied
Interventions
- DEVICE HyperSight cone beam computed tomography (CBCT) scan
- DEVICE ETHOS 2.0
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-04-08 |
| Est. Completion | 2026-04-15 |
What NCT06904365 shows while recruiting
NCT06904365 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (100% lower).
The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which HyperSight cone beam computed tomography (CBCT) scan is the first listed.
NCT06904365 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT06904365 about?
NCT06904365 is a clinical study titled "Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women". Female patients with early onset (\<50 years old) pelvic malignancies such as uterine and rectal cancers are rising in incidence, which often requires pelvic radiation; many of these patients are premenopausal and at a high risk of premature ovarian failure from radiotherapy. Premature ovarian failu...
What is the current status of trial NCT06904365?
This trial is currently recruiting. The enrollment target is 10 participants. The study started on 2025-04-08. Estimated completion is 2026-04-15.
What conditions does trial NCT06904365 study?
This clinical trial studies the following conditions: Breast Cancer, Lung Cancer, Head and Neck Cancer, Sarcoma, Colon Cancer.
What interventions are being tested in trial NCT06904365?
The interventions under investigation include: HyperSight cone beam computed tomography (CBCT) scan (DEVICE), ETHOS 2.0 (DEVICE).
Who is sponsoring clinical trial NCT06904365?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06904365 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06904365's enrollment target sits among peer trials
10 1177th of 1224 higher than 36 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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