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NCT03310138 · ClinicalTrials.gov registry record · Phase 2
RTMS for Treatment of Pain and Craving
A Phase 2 study of Pain, Chronic and Pain, Acute, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- Phase 2
- Development phase
- 22
- Enrollment target
- 1
- Study location
NCT03310138: Completed Phase 2 study of Pain, Chronic and Pain, Acute, sponsored by Medical University of South Carolina.
NCT03310138 is a Phase 2 study of Pain, Chronic and Pain, Acute that has completed, run by Medical University of South Carolina. The registered enrollment target is 22 participants, below the 721-participant average among 48 other Pain, Chronic trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03310138, a Phase 2 study of Pain, Chronic and Pain, Acute, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to develop repetitive transcranial magnetic stimulation (rTMS) as a potential treatment for pain in individuals on prescription opioid medication. Repetitive TMS is a non-invasive technique that uses magnetic pulses to temporarily stimulate specific brain areas in awake people (without the need for surgery, anesthetic, or other invasive procedures). This study will test whether 10 days of rTMS over the prefrontal cortex can produce a reduction in perception of pain and the desire to use opiates. TMS has been approved by the FDA as an investigational tool as well a therapy for depression.
Primary Outcome
Quantitative Sensory Testing will be used to measure each participant's thresholds for sensory detection of heat, painfulness, and tolerance. The investigators will test the hypothesis that Real TMS has a larger effect on thermal pain threshold following 10 days of TMS than sham TMS.
Conditions Studied
Interventions
- DEVICE Sham Transcranial Magnetic Stimulation
- DEVICE Real Transcranial Magnetic Stimulation
Study Locations (1)
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2017-07-06 |
| Est. Completion | 2018-12-12 |
| Phase | Phase 2 |
What the finished NCT03310138 record still lists
NCT03310138 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 721-participant average among 48 other Pain, Chronic trials with a reported enrollment target (97% lower).
The record links to 2 conditions, with Pain, Chronic appearing as the primary indexed condition, and to 2 interventions - of which Sham Transcranial Magnetic Stimulation is the first listed.
NCT03310138 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT03310138 about?
NCT03310138 is a clinical study titled "RTMS for Treatment of Pain and Craving". The purpose of this study is to develop repetitive transcranial magnetic stimulation (rTMS) as a potential treatment for pain in individuals on prescription opioid medication. Repetitive TMS is a non-invasive technique that uses magnetic pulses to temporarily stimulate specific brain areas in awake ...
What is the current status of trial NCT03310138?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 22 participants. The study started on 2017-07-06. Estimated completion is 2018-12-12.
What conditions does trial NCT03310138 study?
This clinical trial studies the following conditions: Pain, Chronic, Pain, Acute.
What interventions are being tested in trial NCT03310138?
The interventions under investigation include: Sham Transcranial Magnetic Stimulation (DEVICE), Real Transcranial Magnetic Stimulation (DEVICE).
Who is sponsoring clinical trial NCT03310138?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03310138 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain, Chronic
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03310138's enrollment target sits among peer trials
22 47th of 48 higher than 2 of 48 other Pain, Chronic trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain, Chronic trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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