Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04828798 · ClinicalTrials.gov registry record · NA
Directional Versus Nondirectional DBS for ET
A NA study of Essential Tremor, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT04828798: Recruiting NA study of Essential Tremor, sponsored by Oregon Health and Science University.
NCT04828798 is a NA study of Essential Tremor that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 24 participants, below the 402-participant average among 41 other Essential Tremor trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04828798, a NA study of Essential Tremor, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
This will be a single center (OHSU) proof of concept trial to demonstrate that directional deep brain stimulation (DBS) creates a larger therapeutic window for the treatment of essential tremor (ET), effectively treats ET, and minimizes effects on speech, gait and balance compared to nondirectional DBS.
Primary Outcome
Range of therapeutic current from clinical improvement to side effect threshold, measured in milliamps, within a range of 0.0 to 5.0 milliamps
Conditions Studied
Interventions
- DEVICE Deep brain stimulation of the VIM Thalamic nuclei
Study Locations (1)
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2021-04-01 |
| Est. Completion | 2029-10-01 |
| Phase | NA |
What NCT04828798 shows while recruiting
NCT04828798 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 402-participant average among 41 other Essential Tremor trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Essential Tremor appearing as the primary indexed condition, and to 1 intervention - of which Deep brain stimulation of the VIM Thalamic nuclei is the first listed.
NCT04828798 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT04828798 about?
NCT04828798 is a clinical study titled "Directional Versus Nondirectional DBS for ET". This will be a single center (OHSU) proof of concept trial to demonstrate that directional deep brain stimulation (DBS) creates a larger therapeutic window for the treatment of essential tremor (ET), effectively treats ET, and minimizes effects on speech, gait and balance compared to nondirectional ...
What is the current status of trial NCT04828798?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2021-04-01. Estimated completion is 2029-10-01.
What conditions does trial NCT04828798 study?
This clinical trial studies the following conditions: Essential Tremor.
What interventions are being tested in trial NCT04828798?
The interventions under investigation include: Deep brain stimulation of the VIM Thalamic nuclei (DEVICE).
Who is sponsoring clinical trial NCT04828798?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04828798 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Essential Tremor
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04828798's enrollment target sits among peer trials
24 31st of 41 higher than 10 of 41 other Essential Tremor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Essential Tremor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Circadian Adaptive DBS in Essential Tremor
RECRUITING · NA
-
Motor Network Physiology
RECRUITING · NA
-
Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients
RECRUITING · NA
-
3-D Tractography FUS Ablation for Essential Tremor
RECRUITING · NA
-
Elucidating the Temporality of Structural and Functional Connectivity Changes in Essential Tremor After Successful Deep Brain Stimulation to the Dentato-rubro-thalamic Tract
RECRUITING · NA
-
Algorithms for Programming DBS Systems for ET
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02331979 · 24 participants · NA
Improving Bladder Function in SCI by Neuromodulation
- NCT03096197 · 24 participants · NA
Exoskeleton and Spinal Cord Stimulation for SCI
- NCT03223922 · 24 participants · NA
Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases
- NCT03326921 · 24 participants · Phase 1
HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI