Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

RECRUITING Phase 3

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

NCT06203210 · View on ClinicalTrials.gov ↗

Study Summary

This study was designed to compare the efficacy and safety of I-DXd with treatment of physician's choice in participants with relapsed small cell lung cancer (SCLC).

Conditions Studied

Interventions

  • DRUG Topotecan
  • DRUG Lurbinectedin
  • DRUG Ifinatamab deruxtecan
  • DRUG Amrubicin

Study Locations (20)

California

  • Clinical Research Providence Medical Foundation — Fullerton
  • UCLA Hematology-Oncology — Los Angeles
  • UCSF Mission Bay Mission Hall — San Francisco

Florida

  • University of Miami Hospital and Clinics Sylvester Comprehensive Cancer Center — Miami
  • AdventHealth Orlando, Cancer Institute — Orlando
  • H. Lee Moffitt Cancer Center and Research Institute, Inc — Tampa

Maryland

  • University of Maryland Greenebaum Comprehensive Cancer Center — Baltimore
  • John Hopkins School of Medicine — Baltimore

New Jersey

  • Astera Cancer Care — East Brunswick
  • Meridian Health Systems — Neptune City

New York

  • Clinical Research Alliance, Inc — Lake Success
  • New York University Cancer Center - Laura and Isaac — New York

Arkansas

  • Highlands Oncology Group — Springdale

Illinois

  • Rush MD Anderson Cancer Center — Chicago

Kentucky

  • Baptist Health Lexington — Lexington

Trial Details

FieldValue
Enrollment Target 540 participants
Start Date 2024-05-21
Est. Completion 2029-02-22
Phase Phase 3

Sponsor

Daiichi Sankyo

157 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06203210

The ClinicalTrials.gov registry entry for NCT06203210 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 540 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Daiichi Sankyo, which has 157 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Small Cell Lung Cancer appearing as the primary indexed condition, and to 4 interventions — of which Topotecan is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06203210 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Florida, Maryland. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06203210 about?

NCT06203210 is a clinical study titled "A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer". This study was designed to compare the efficacy and safety of I-DXd with treatment of physician's choice in participants with relapsed small cell lung cancer (SCLC).

What is the current status of trial NCT06203210?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 540 participants. The study started on 2024-05-21. Estimated completion is 2029-02-22.

What conditions does trial NCT06203210 study?

This clinical trial studies the following conditions: Small Cell Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06203210?

The interventions under investigation include: Topotecan (DRUG), Lurbinectedin (DRUG), Ifinatamab deruxtecan (DRUG), Amrubicin (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06203210?

This trial is sponsored by Daiichi Sankyo, which has 157 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06203210 being conducted?

This trial has 20 study locations across Arkansas, California, Florida, Illinois, Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial