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A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)
NCT07218146 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to evaluate the efficacy and safety of ZL-1310 compared to Investigator's Choice Therapy in participants with relapsed Small Cell Lung Cancer.
Conditions Studied
Interventions
- DRUG ZL-1310
- DRUG Investigator's Choice of Therapy
Study Locations (14)
Florida
- Zai Lab Site 02045 — Clermont
- Zai Lab Site 02031 — Orange City
- Zai Lab Site 02020 — Rockledge
- Zai Lab Site 02026 — Sarasota
Illinois
- Zai Lab Site 02021 — Peoria
- Zai Lab Site 02049 — Peoria
Pennsylvania
- Zai Lab Site 02035 — Broomall
- Zai Lab Site 02019 — Media
Kentucky
- Zai Lab Site 02041 — Louisville
Maryland
- Zai Lab Site 02003 — Bethesda
Missouri
- Zai Lab Site 02023 — Columbia
Tennessee
- Zai Lab Site 02036 — Nashville
Texas
- Zai Lab Site 02025 — Odessa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 480 participants |
| Start Date | 2025-11-30 |
| Est. Completion | 2028-11-30 |
| Phase | Phase 3 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07218146
The ClinicalTrials.gov registry entry for NCT07218146 describes a study currently listed as recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 480 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Zai Lab (Shanghai) Co., which has 33 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Small-cell Lung Cancer appearing as the primary indexed condition, and to 2 interventions — of which ZL-1310 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07218146 reports 14 study locations spanning 9 distinct geographic areas — top geographies include Florida, Illinois, Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07218146 about?
NCT07218146 is a clinical study titled "A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE)". The purpose of this study is to evaluate the efficacy and safety of ZL-1310 compared to Investigator's Choice Therapy in participants with relapsed Small Cell Lung Cancer.
What is the current status of trial NCT07218146?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 480 participants. The study started on 2025-11-30. Estimated completion is 2028-11-30.
What conditions does trial NCT07218146 study?
This clinical trial studies the following conditions: Small-cell Lung Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07218146?
The interventions under investigation include: ZL-1310 (DRUG), Investigator's Choice of Therapy (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07218146?
This trial is sponsored by Zai Lab (Shanghai) Co., which has 33 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07218146 being conducted?
This trial has 14 study locations across Florida, Illinois, Kentucky, Maryland, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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