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RECRUITING Phase 1

Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease

NCT02447874 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this study is to determine whether giving extra arginine to patients with sickle cell disease seeking treatment for vaso-occlusive painful events (VOE) will decrease pain scores, decrease need for pain medications or decrease length of hospital stay or emergency department visit.

Conditions Studied

Interventions

  • DRUG Arginine
  • DRUG Arginine (Loading)
  • DRUG Arginine (Continuous)

Study Locations (2)

Georgia

  • Children's Healthcare fo Atlanta at Hughes Spalding — Atlanta
  • Children's Healthcare of Atlanta at Arthur M. Blank Hospital — Atlanta

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2015-05
Est. Completion 2026-07
Phase Phase 1

Sponsor

Emory University

1,434 total trials

Interested in This Trial?

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT02447874

The ClinicalTrials.gov registry entry for NCT02447874 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Emory University, which has 1,434 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Sickle Cell Disease appearing as the primary indexed condition, and to 3 interventions — of which Arginine is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT02447874 reports 2 study locations spanning 1 distinct geographic area — top geographies include Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT02447874 about?

NCT02447874 is a clinical study titled "Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease". The purpose of this study is to determine whether giving extra arginine to patients with sickle cell disease seeking treatment for vaso-occlusive painful events (VOE) will decrease pain scores, decrease need for pain medications or decrease length of hospital stay or emergency department visit.

What is the current status of trial NCT02447874?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2015-05. Estimated completion is 2026-07.

What conditions does trial NCT02447874 study?

This clinical trial studies the following conditions: Sickle Cell Disease. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT02447874?

The interventions under investigation include: Arginine (DRUG), Arginine (Loading) (DRUG), Arginine (Continuous) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT02447874?

This trial is sponsored by Emory University, which has 1,434 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT02447874 being conducted?

This trial has 2 study locations across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial