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NCT05412810 · ClinicalTrials.gov registry record
Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).
A clinical trial of Mechanical Ventilation Complication and Hyperoxia, sponsored by Ohio State University.
- Recruiting
- Registry status
- 200
- Enrollment target
- 1
- Study location
NCT05412810: Recruiting study of Mechanical Ventilation Complication and Hyperoxia, sponsored by Ohio State University.
NCT05412810 is a study of Mechanical Ventilation Complication and Hyperoxia that is actively recruiting participants, run by Ohio State University. The registered enrollment target is 200 participants, below the 1,164-participant average among 8 other Mechanical Ventilation Complication trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05412810, a study of Mechanical Ventilation Complication and Hyperoxia, is actively recruiting participants, sponsored by Ohio State University.
- RECRUITING
- Registry status
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
The aim of this study is to identify and determine the levels of oxidized lipids and lipid mediators following exposure to oxygen supplementation during mechanical ventilation by oxidative lipidomics. The investigators will include patients with mechanical ventilation and have received FiO2=\>0.5 atleast 90 minutes and collected two sequential mini bronchoalveolar lavage on them 24 hours apart. Mass Spectrometry Lipid chromatography will be conducted and clinical data will be analyzed.
Conditions Studied
Interventions
- OTHER oxygen
Study Locations (1)
Ohio
- Ohio State University Medical Center - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2023-03-01 |
| Est. Completion | 2026-09-01 |
What NCT05412810 shows while recruiting
NCT05412810 is an observational study that tracks outcomes without assigning an intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, below the 1,164-participant average among 8 other Mechanical Ventilation Complication trials with a reported enrollment target (83% lower).
The record links to 2 conditions, with Mechanical Ventilation Complication appearing as the primary indexed condition, and to 1 intervention - of which oxygen is the first listed.
NCT05412810 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05412810 about?
NCT05412810 is a clinical study titled "Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).". The aim of this study is to identify and determine the levels of oxidized lipids and lipid mediators following exposure to oxygen supplementation during mechanical ventilation by oxidative lipidomics. The investigators will include patients with mechanical ventilation and have received FiO2=\>0.5 at...
What is the current status of trial NCT05412810?
This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2023-03-01. Estimated completion is 2026-09-01.
What conditions does trial NCT05412810 study?
This clinical trial studies the following conditions: Mechanical Ventilation Complication, Hyperoxia.
What interventions are being tested in trial NCT05412810?
The interventions under investigation include: oxygen (OTHER).
Who is sponsoring clinical trial NCT05412810?
This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05412810 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Mechanical Ventilation Complication
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05412810's enrollment target sits among peer trials
200 4th of 8 higher than 5 of 8 other Mechanical Ventilation Complication trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mechanical Ventilation Complication trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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