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NCT05412810 · ClinicalTrials.gov registry record

Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).

A clinical trial of Mechanical Ventilation Complication and Hyperoxia, sponsored by Ohio State University.

Recruiting
Registry status
200
Enrollment target
1
Study location

NCT05412810 is a study of Mechanical Ventilation Complication and Hyperoxia that is actively recruiting participants, run by Ohio State University. The registered enrollment target is 200 participants, below the 1,164-participant average among 8 other Mechanical Ventilation Complication trials with a reported enrollment target (83% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT05412810, a study of Mechanical Ventilation Complication and Hyperoxia, is actively recruiting participants, sponsored by Ohio State University.

RECRUITING
Registry status
200 participants
Enrollment target
1
Study location

Study Summary

The aim of this study is to identify and determine the levels of oxidized lipids and lipid mediators following exposure to oxygen supplementation during mechanical ventilation by oxidative lipidomics. The investigators will include patients with mechanical ventilation and have received FiO2=\>0.5 atleast 90 minutes and collected two sequential mini bronchoalveolar lavage on them 24 hours apart. Mass Spectrometry Lipid chromatography will be conducted and clinical data will be analyzed.

Interventions

  • OTHER oxygen

Study Locations (1)

Ohio

  • Ohio State University Medical Center - Columbus

Trial Details

FieldValue
Enrollment Target 200 participants
Start Date 2023-03-01
Est. Completion 2026-09-01

Sponsor

Ohio State University

552 total trials

What the Registry Record Tells You About NCT05412810

The ClinicalTrials.gov registry entry for NCT05412810 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,164-participant average among 8 other Mechanical Ventilation Complication trials with a reported enrollment target (83% lower). The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Mechanical Ventilation Complication appearing as the primary indexed condition, and to 1 intervention - of which oxygen is the first listed.

NCT05412810 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT05412810 about?

NCT05412810 is a clinical study titled "Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).". The aim of this study is to identify and determine the levels of oxidized lipids and lipid mediators following exposure to oxygen supplementation during mechanical ventilation by oxidative lipidomics. The investigators will include patients with mechanical ventilation and have received FiO2=\>0.5 at...

What is the current status of trial NCT05412810?

This trial is currently recruiting. The enrollment target is 200 participants. The study started on 2023-03-01. Estimated completion is 2026-09-01.

What conditions does trial NCT05412810 study?

This clinical trial studies the following conditions: Mechanical Ventilation Complication, Hyperoxia.

What interventions are being tested in trial NCT05412810?

The interventions under investigation include: oxygen (OTHER).

Who is sponsoring clinical trial NCT05412810?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05412810 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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