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NCT06338267 · ClinicalTrials.gov registry record

Validating Innovative Biosensors for Rett Autonomic Symptom Tracking

A clinical trial of Rett Syndrome, sponsored by Rett Syndrome Research Trust.

Recruiting
Registry status
30
Enrollment target
3
Study locations

NCT06338267 is a study of Rett Syndrome that is actively recruiting participants, run by Rett Syndrome Research Trust. The registered enrollment target is 30 participants, below the 524-participant average among 18 other Rett Syndrome trials with a reported enrollment target (94% lower). The trial reports 3 study locations across 3 states.

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The verdict

NCT06338267, a study of Rett Syndrome, is actively recruiting participants, sponsored by Rett Syndrome Research Trust.

RECRUITING
Registry status
30 participants
Enrollment target
3
Study locations

Study Summary

The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials. VIBRANT will use several FDA-cleared wearable biosensors and a non-wearable device to collect symptom data from patients with Rett syndrome for up to 9 weeks. Symptoms of interest include heart rate, breathing, sleep, blood oxygen levels, and movement. Participants will use the biosensors intermittently at home, document device use and symptom status, and will come to the clinic for 1 overnight sleep study. A cohort of up to 10 participants receiving an intervention in a separate clinical trial may also enroll and participate on a custom device schedule for up to 1 year. The study will provide information on the feasibility and ease of use for families at home, biosensor data will be compared to data collected at the same time from the overnight sleep study to demonstrate how well they work in individuals with Rett syndrome, and Emerald will be developed to include movement as a measurable symptom.

Conditions Studied

Study Locations (3)

Illinois

  • Rush University Medical Center - Chicago

Massachusetts

  • Boston Children's Hospital - Boston

Texas

  • Baylor College of Medicine - Houston

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-03-03
Est. Completion 2026-06

Sponsor

Rett Syndrome Research Trust

5 total trials

What the Registry Record Tells You About NCT06338267

The ClinicalTrials.gov registry entry for NCT06338267 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 524-participant average among 18 other Rett Syndrome trials with a reported enrollment target (94% lower). The listed sponsor is Rett Syndrome Research Trust, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Rett Syndrome appearing as the primary indexed condition, and to 0 interventions.

NCT06338267 reports 3 study locations spanning 3 distinct geographic areas - top geographies include Illinois, Massachusetts, Texas.

Frequently Asked Questions

What is clinical trial NCT06338267 about?

NCT06338267 is a clinical study titled "Validating Innovative Biosensors for Rett Autonomic Symptom Tracking". The VIBRANT study aims to validate biosensors to objectively and directly measure symptoms in Rett syndrome and create confidence in the use of these devices in clinical trials. VIBRANT will use several FDA-cleared wearable biosensors and a non-wearable device to collect symptom data from patients w...

What is the current status of trial NCT06338267?

This trial is currently recruiting. The enrollment target is 30 participants. The study started on 2025-03-03. Estimated completion is 2026-06.

What conditions does trial NCT06338267 study?

This clinical trial studies the following conditions: Rett Syndrome.

Who is sponsoring clinical trial NCT06338267?

This trial is sponsored by Rett Syndrome Research Trust, which has 5 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06338267 being conducted?

This trial has 3 study locations across Illinois, Massachusetts, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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