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NCT03153683 · ClinicalTrials.gov registry record
Brain, Blood And Clot or Tissue Registry And Collaboration
A clinical trial of Acute Ischemic Stroke and Cerebrovascular Disorders, sponsored by Justin Fraser.
- Recruiting
- Registry status
- 1,000
- Enrollment target
- 1
- Study location
NCT03153683: Recruiting study of Acute Ischemic Stroke and Cerebrovascular Disorders, sponsored by Justin Fraser.
NCT03153683 is a study of Acute Ischemic Stroke and Cerebrovascular Disorders that is actively recruiting participants, run by Justin Fraser. The registered enrollment target is 1,000 participants, above the 312-participant average among 25 other Acute Ischemic Stroke trials with a reported enrollment target (221% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03153683, a study of Acute Ischemic Stroke and Cerebrovascular Disorders, is actively recruiting participants, sponsored by Justin Fraser.
- RECRUITING
- Registry status
- 1,000 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a prospective open enrollment biorepository to collect and evaluate blood and tissue collected during cerebrovascular procedures, which will then be used for the purposes of identifying biological markers, inflammatory cell infiltrates, and biological states in stroke and other cerebrovascular diseases in the human condition. The study population will include up to 1000 subjects with cerebrovascular disease or suspected cerebrovascular disease. Male and female participants 18 years of age and older will be enrolled. This protocol covers the procurement of biological samples from patients undergoing any cerebrovascular surgery and/or neurointerventional clinical procedure at University of Kentucky. Control participants will include patients undergoing non-emergent, elective diagnostic cerebral angiography as well as patients undergoing emergent angiogram cases. This study represents the first time that tissue, clot and blood will be evaluated for the markers, proteins, and cytokines in human subjects undergoing cerebrovascular procedures. By starting with the human condition, the investigators aim to minimize this loss in translation. Overall, this study will have a great impact on our knowledge of stroke pathology. In essence, this could fundamentally change not only how the investigators develop treatment strategies for the stroke patient population but allow us to individualize the treatment dependent on time after stroke, age, sex, and co-morbidities. Molecular techniques that are impractical when delivered systemically could be delivered locally to impede the early inflammation. This research aims to advance understanding of cerebrovascular disease and to support the development of improved therapies.
Primary Outcome
A small amount of blood (from the two specimens) will be sent for blood gas analysis to evaluate the pH, pO2, pCO2, pHCO3 potassium, sodium, and calcium concentrations.
Conditions Studied
Interventions
- OTHER Registry
Study Locations (1)
Kentucky
- University of Kentucky Deparment of Neurosurgery, UK Chandler Hospital - Lexington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2017-05-11 |
| Est. Completion | 2029-12-28 |
What NCT03153683 shows while recruiting
NCT03153683 is an observational study that tracks outcomes without assigning an intervention. Its 1,000 participants enrollment target places it among the larger protocols in the corpus, above the 312-participant average among 25 other Acute Ischemic Stroke trials with a reported enrollment target (221% higher).
The record links to 2 conditions, with Acute Ischemic Stroke appearing as the primary indexed condition, and to 1 intervention - of which Registry is the first listed.
NCT03153683 reports a single indexed study location in Kentucky.
Frequently Asked Questions
What is clinical trial NCT03153683 about?
NCT03153683 is a clinical study titled "Brain, Blood And Clot or Tissue Registry And Collaboration". This is a prospective open enrollment biorepository to collect and evaluate blood and tissue collected during cerebrovascular procedures, which will then be used for the purposes of identifying biological markers, inflammatory cell infiltrates, and biological states in stroke and other cerebrovascul...
What is the current status of trial NCT03153683?
This trial is currently recruiting. The enrollment target is 1,000 participants. The study started on 2017-05-11. Estimated completion is 2029-12-28.
What conditions does trial NCT03153683 study?
This clinical trial studies the following conditions: Acute Ischemic Stroke, Cerebrovascular Disorders.
What interventions are being tested in trial NCT03153683?
The interventions under investigation include: Registry (OTHER).
Who is sponsoring clinical trial NCT03153683?
This trial is sponsored by Justin Fraser, which has 4 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03153683 being conducted?
This trial has 1 study location across Kentucky. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Acute Ischemic Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03153683's enrollment target sits among peer trials
1,000 2nd of 25 higher than 23 of 25 other Acute Ischemic Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acute Ischemic Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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