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NCT07435662 · ClinicalTrials.gov registry record · NA
Optimizing Heart Failure Therapies Among Patients With Limited Access in Denver
A NA study of Heart Failure and Medication Optimization, sponsored by Denver Health and Hospital Authority.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07435662 is a NA study of Heart Failure and Medication Optimization that is actively recruiting participants, run by Denver Health and Hospital Authority. The registered enrollment target is 40 participants, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07435662, a NA study of Heart Failure and Medication Optimization, is actively recruiting participants, sponsored by Denver Health and Hospital Authority.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Numerous pharmacotherapies have been proven to reduce mortality and hospitalization rates for heart failure with reduced ejection fraction (HFrEF) patients. However, these are underutilized clinically, preventing realization of proven benefits. Simplified patient education tools and multidisciplinary teams including pharmacists have been used to improve medication optimization but in predominantly private payer groups. This study will translate these evidence-based interventions to patients with limited access to care. In this randomized, prospective study, patients with HFrEF at a local hospital dedicated to care for participants with limited access will receive either pharmacist-directed medication adjustment visits with patient education materials or standard of care. This study will assess the hypothesis that the implementation of the intervention is feasible in this population, as demonstrated by the number of visits and proportion of visits with medication adjustments. Further, medication dosing in each arm will be evaluated via the Kansas City Medication Optimization (KCMO) score, which will average the percentage of maximal doses of appropriate HFrEF medication classes a patient is on. The change in KCMO scores over the course of the pilot in the two arms will then be compared to assess the hypothesis that the intervention will better increase patients' KCMO scores than the standard of care. The findings of this study will help address knowledge gaps in the care of patients not well represented previously in the literature. This proposal addresses the translational science roadblock of recruitment and engagement of participants with limited access to care.
Conditions Studied
Interventions
- OTHER Pharmacy follow up
Study Locations (1)
Colorado
- Denver Health and Hospital Authority - Denver
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2026-07-01 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07435662
The ClinicalTrials.gov registry entry for NCT07435662 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,049-participant average among 397 other Heart Failure trials with a reported enrollment target (98% lower). The listed sponsor is Denver Health and Hospital Authority, which has 73 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Heart Failure appearing as the primary indexed condition, and to 1 intervention - of which Pharmacy follow up is the first listed.
NCT07435662 reports 1 study location spanning 1 distinct geographic area - top geographies include Colorado.
Frequently Asked Questions
What is clinical trial NCT07435662 about?
NCT07435662 is a clinical study titled "Optimizing Heart Failure Therapies Among Patients With Limited Access in Denver". Numerous pharmacotherapies have been proven to reduce mortality and hospitalization rates for heart failure with reduced ejection fraction (HFrEF) patients. However, these are underutilized clinically, preventing realization of proven benefits. Simplified patient education tools and multidisciplinar...
What is the current status of trial NCT07435662?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-10-01. Estimated completion is 2026-07-01.
What conditions does trial NCT07435662 study?
This clinical trial studies the following conditions: Heart Failure, Medication Optimization.
What interventions are being tested in trial NCT07435662?
The interventions under investigation include: Pharmacy follow up (OTHER).
Who is sponsoring clinical trial NCT07435662?
This trial is sponsored by Denver Health and Hospital Authority, which has 73 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07435662 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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