Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Endocrine System Diseases

Open-data reference.

12 US clinical trials · 4 currently recruiting

Active & Recent Trials

RECRUITING 2,000 participants

Rare and Atypical Diabetes Network

University of South Florida

NCT05544266

RECRUITING Phase 2 75 participants

Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Sling Therapeutics

NCT06112340

RECRUITING NA 60 participants

In-Person Lifestyle Program for Black Adolescent Girls at Risk for Type 2 Diabetes

Cornell University

NCT06557317

RECRUITING Phase 2 21 participants

Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury

North Florida Foundation for Research and Education

NCT04460872

ACTIVE NOT RECRUITING Phase 3 165 participants

Evaluation of the Safety and Efficacy of Eneboparatide (AZP-3601) in Patients With Chronic Hypoparathyroidism

Alexion Pharmaceuticals

NCT05778071

ACTIVE NOT RECRUITING Phase 2 90 participants

A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Sling Therapeutics

NCT05276063

ACTIVE NOT RECRUITING 46 participants

Intestinal Metabolic Reprogramming as a Key Mechanism of Gastric Bypass in Humans

University of Pittsburgh

NCT02710370

COMPLETED Phase 3 866 participants

Nab-paclitaxel and Gemcitabine vs Gemcitabine Alone as Adjuvant Therapy for Patients With Resected Pancreatic Cancer (the "Apact" Study)

Celgene

NCT01964430

COMPLETED Phase 3 264 participants

A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropin Product in Adults With Growth Hormone Deficiency

Ascendis Pharma Endocrinology Division A/S

NCT04615273

COMPLETED NA 131 participants

Day and Night Closed-loop in Young People With Type 1 Diabetes

Jaeb Center for Health Research

NCT02925299

COMPLETED Phase 1 84 participants

Single-Dose And Multiple-Dose Safety And Tolerability Study Of PF-04856883 In Type 2 Diabetic Adult Females

Pfizer

NCT01301456

COMPLETED Phase 1 39 participants

First-In-Human Study of GFB-024 in Healthy Overweight and Obese Participants, and Participants With Type 2 Diabetes

Goldfinch Bio

NCT04880291

Phase Distribution

PhaseTrial count
Early Phase 1 2
Phase 2 3
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Endocrine System Diseases Trial Landscape

ClinicalTrials.gov lists 12 US studies indexed under Endocrine System Diseases, and 4 of those are currently open to recruitment — roughly 33% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Endocrine System Diseases shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Endocrine System Diseases is led by Sling Therapeutics with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 12 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Endocrine System Diseases?

PlainTrial tracks 12 US clinical trials for Endocrine System Diseases, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Endocrine System Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →