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NCT05543083 · ClinicalTrials.gov registry record · NA

Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes

A NA study of Depression and Insulin Resistance, sponsored by Colorado State University.

Recruiting
Registry status
NA
Development phase
300
Enrollment target
2
Study locations

NCT05543083: Recruiting NA study of Depression and Insulin Resistance, sponsored by Colorado State University.

NCT05543083 is a NA study of Depression and Insulin Resistance that is actively recruiting participants, run by Colorado State University. The registered enrollment target is 300 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (62% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05543083, a NA study of Depression and Insulin Resistance, is actively recruiting participants, sponsored by Colorado State University.

RECRUITING
Registry status
NA
Development phase
300 participants
Enrollment target
2
Study locations

Study Summary

The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or a combination of cognitive-behavioral therapy and exercise training groups, decreases stress, improves mood, increases physical activity and physical fitness, and decreases insulin resistance among teenagers at risk for diabetes.

Primary Outcome

Homeostatic model assessment of insulin resistance (HOMA-IR) estimated from fasting insulin and glucose as part of oral glucose tolerance testing

Conditions Studied

Depression Insulin Resistance Depressive Disorder Mood Disorders Metabolic Disease Glucose Metabolism Disorders Hyperinsulinism Mental Disorder in Adolescence

Interventions

  • BEHAVIORAL Cognitive-Behavioral Therapy followed by Exercise Training
  • BEHAVIORAL Exercise Training followed by Cognitive-Behavioral Therapy
  • BEHAVIORAL Cognitive-Behavioral Therapy Only
  • BEHAVIORAL Exercise Training Only

Study Locations (2)

Colorado

  • Children's Hospital Colorado - Aurora
  • Colorado State University - Fort Collins

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2023-06-02
Est. Completion 2029-03-31
Phase NA
Colorado State University

94 total trials

What NCT05543083 shows while recruiting

NCT05543083 is an interventional study that assigns participants to a tested intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (62% lower).

The record links to 8 conditions, with Depression appearing as the primary indexed condition, and to 4 interventions - of which Cognitive-Behavioral Therapy followed by Exercise Training is the first listed.

NCT05543083 reports a single indexed study location in Colorado.

Frequently Asked Questions

What is clinical trial NCT05543083 about?

NCT05543083 is a clinical study titled "Cognitive-Behavioral Therapy and Exercise Training in Adolescents At-Risk for Type 2 Diabetes". The investigators are doing this study to learn more about how to prevent type 2 diabetes in teenage girls. The purpose of this study is to find out if taking part in a cognitive-behavioral therapy group, exercise training group, or a combination of cognitive-behavioral therapy and exercise training...

What is the current status of trial NCT05543083?

This trial is currently recruiting. It is a NA study. The enrollment target is 300 participants. The study started on 2023-06-02. Estimated completion is 2029-03-31.

What conditions does trial NCT05543083 study?

This clinical trial studies the following conditions: Depression, Insulin Resistance, Depressive Disorder, Mood Disorders, Metabolic Disease.

What interventions are being tested in trial NCT05543083?

The interventions under investigation include: Cognitive-Behavioral Therapy followed by Exercise Training (BEHAVIORAL), Exercise Training followed by Cognitive-Behavioral Therapy (BEHAVIORAL), Cognitive-Behavioral Therapy Only (BEHAVIORAL), Exercise Training Only (BEHAVIORAL).

Who is sponsoring clinical trial NCT05543083?

This trial is sponsored by Colorado State University, which has 94 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05543083 being conducted?

This trial has 2 study locations across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Depression

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05543083's enrollment target sits among peer trials

300 140th of 679 higher than 533 of 679 other Depression trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT05543083

Source: ClinicalTrials.gov NCT05543083, the US trial registry maintained by the National Library of Medicine. NCT05543083 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.