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NCT04743271 · ClinicalTrials.gov registry record · NA
Food and Circadian Timing
A NA study of Circadian Rhythm and Diet, High-Fat, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- NA
- Development phase
- 14
- Enrollment target
- 1
- Study location
NCT04743271: Recruiting NA study of Circadian Rhythm and Diet, High-Fat, sponsored by Oregon Health and Science University.
NCT04743271 is a NA study of Circadian Rhythm and Diet, High-Fat that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 14 participants, below the 95-participant average among 9 other Circadian Rhythm trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04743271, a NA study of Circadian Rhythm and Diet, High-Fat, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- NA
- Development phase
- 14 participants
- Enrollment target
- 1
- Study location
Study Summary
The goals of this study are to uncover the influence of diet on the human circadian timing system. The protocol is a 46-day (28 outpatient days, 18 inpatient days over two 9 day visits) randomized cross-over study designed to elucidate the speed of entrainment in response to a high-fat diet.
Primary Outcome
Entrainment will be determined as a stable phase angle between sleep and both melatonin onset. Blood and/or saliva will be assayed for melatonin using standardized assays. Melatonin onset will be calculated using the linear interpolated time at which melatonin levels reach 25% of a fitted peak-to-trough amplitude. This will be analyzed using phase angle between sleep and melatonin onset.
Conditions Studied
Interventions
- OTHER High-Fat Diet
- OTHER Low-Fat Diet
Study Locations (1)
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 14 participants |
| Start Date | 2022-04-01 |
| Est. Completion | 2026-03-31 |
| Phase | NA |
What NCT04743271 shows while recruiting
NCT04743271 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 95-participant average among 9 other Circadian Rhythm trials with a reported enrollment target (85% lower).
The record links to 2 conditions, with Circadian Rhythm appearing as the primary indexed condition, and to 2 interventions - of which High-Fat Diet is the first listed.
NCT04743271 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT04743271 about?
NCT04743271 is a clinical study titled "Food and Circadian Timing". The goals of this study are to uncover the influence of diet on the human circadian timing system. The protocol is a 46-day (28 outpatient days, 18 inpatient days over two 9 day visits) randomized cross-over study designed to elucidate the speed of entrainment in response to a high-fat diet.
What is the current status of trial NCT04743271?
This trial is currently recruiting. It is a NA study. The enrollment target is 14 participants. The study started on 2022-04-01. Estimated completion is 2026-03-31.
What conditions does trial NCT04743271 study?
This clinical trial studies the following conditions: Circadian Rhythm, Diet, High-Fat.
What interventions are being tested in trial NCT04743271?
The interventions under investigation include: High-Fat Diet (OTHER), Low-Fat Diet (OTHER).
Who is sponsoring clinical trial NCT04743271?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04743271 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Circadian Rhythm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04743271's enrollment target sits among peer trials
14 9th of 9 higher than 1 of 9 other Circadian Rhythm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Circadian Rhythm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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