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NCT02090140 · ClinicalTrials.gov registry record · NA
Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
A NA study of Degenerative Lesion of Articular Cartilage of Knee, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- NA
- Development phase
- 17
- Enrollment target
- 3
- Study locations
NCT02090140: Recruiting NA study of Degenerative Lesion of Articular Cartilage of Knee, sponsored by University of Colorado, Denver.
NCT02090140 is a NA study of Degenerative Lesion of Articular Cartilage of Knee that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 17 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02090140, a NA study of Degenerative Lesion of Articular Cartilage of Knee, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- NA
- Development phase
- 17 participants
- Enrollment target
- 3
- Study locations
Study Summary
The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the subchondral bone marrow to the site of cartilage loss. The second method is the application of adipose-derived stem cells (ADSCs) to the defect site. In theory, ADSCs on a collagen scaffold should enable the delivery of more specific progenitor cells to the site of injury, resulting in better regeneration and integration of articular cartilage at the site of a defect as compared to the microfracture method.
Conditions Studied
Interventions
- PROCEDURE ADSC Application
- PROCEDURE Microfracture
Study Locations (3)
California
- Stanford Medical Outpatient Center - Redwood City
- Kerlan Jobe Orthopedic Institute - Santa Monica
Colorado
- UC Health Steadman Hawkins Clinic - Denver Inverness - Denver
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2015-11 |
| Est. Completion | 2025-12 |
| Phase | NA |
What NCT02090140 shows while recruiting
NCT02090140 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Degenerative Lesion of Articular Cartilage of Knee appearing as the primary indexed condition, and to 2 interventions - of which ADSC Application is the first listed.
NCT02090140 reports a single indexed study location in California, Colorado.
Frequently Asked Questions
What is clinical trial NCT02090140 about?
NCT02090140 is a clinical study titled "Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects". The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the subchondral bone marrow to the site of cartilage loss. The second method...
What is the current status of trial NCT02090140?
This trial is currently recruiting. It is a NA study. The enrollment target is 17 participants. The study started on 2015-11. Estimated completion is 2025-12.
What conditions does trial NCT02090140 study?
This clinical trial studies the following conditions: Degenerative Lesion of Articular Cartilage of Knee.
What interventions are being tested in trial NCT02090140?
The interventions under investigation include: ADSC Application (PROCEDURE), Microfracture (PROCEDURE).
Who is sponsoring clinical trial NCT02090140?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02090140 being conducted?
This trial has 3 study locations across California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02090140's enrollment target sits among peer trials
17 1871st of 2000 higher than 130 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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