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NCT02090140 · ClinicalTrials.gov registry record · NA

Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects

A NA study of Degenerative Lesion of Articular Cartilage of Knee, sponsored by University of Colorado, Denver.

Recruiting
Registry status
NA
Development phase
17
Enrollment target
3
Study locations

NCT02090140 is a NA study of Degenerative Lesion of Articular Cartilage of Knee that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 17 participants. The trial reports 3 study locations across 2 states.

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The verdict

NCT02090140, a NA study of Degenerative Lesion of Articular Cartilage of Knee, is actively recruiting participants, sponsored by University of Colorado, Denver.

RECRUITING
Registry status
NA
Development phase
17 participants
Enrollment target
3
Study locations

Study Summary

The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the subchondral bone marrow to the site of cartilage loss. The second method is the application of adipose-derived stem cells (ADSCs) to the defect site. In theory, ADSCs on a collagen scaffold should enable the delivery of more specific progenitor cells to the site of injury, resulting in better regeneration and integration of articular cartilage at the site of a defect as compared to the microfracture method.

Interventions

  • PROCEDURE ADSC Application
  • PROCEDURE Microfracture

Study Locations (3)

California

  • Stanford Medical Outpatient Center - Redwood City
  • Kerlan Jobe Orthopedic Institute - Santa Monica

Colorado

  • UC Health Steadman Hawkins Clinic - Denver Inverness - Denver

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2015-11
Est. Completion 2025-12
Phase NA

Sponsor

University of Colorado, Denver

1,283 total trials

What the Registry Record Tells You About NCT02090140

The ClinicalTrials.gov registry entry for NCT02090140 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Degenerative Lesion of Articular Cartilage of Knee appearing as the primary indexed condition, and to 2 interventions - of which ADSC Application is the first listed.

NCT02090140 reports 3 study locations spanning 2 distinct geographic areas - top geographies include California, Colorado.

Frequently Asked Questions

What is clinical trial NCT02090140 about?

NCT02090140 is a clinical study titled "Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects". The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the subchondral bone marrow to the site of cartilage loss. The second method...

What is the current status of trial NCT02090140?

This trial is currently recruiting. It is a NA study. The enrollment target is 17 participants. The study started on 2015-11. Estimated completion is 2025-12.

What conditions does trial NCT02090140 study?

This clinical trial studies the following conditions: Degenerative Lesion of Articular Cartilage of Knee.

What interventions are being tested in trial NCT02090140?

The interventions under investigation include: ADSC Application (PROCEDURE), Microfracture (PROCEDURE).

Who is sponsoring clinical trial NCT02090140?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02090140 being conducted?

This trial has 3 study locations across California, Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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