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ACP-196 Versus Placebo in Subjects With Rheumatoid Arthritis on Background Methotrexate
NCT02387762 · View on ClinicalTrials.gov ↗
Study Summary
This study is evaluating the safety, pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of ACP-196 in subjects with Rheumatoid Arthritis on background Methotrexate.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG acalabrutinib
Study Locations (17)
California
- TriWest Research Associates, LLC — El Cajon
- Neuropsychiatric Research Center of Orange County — Orange
- Pacific Arthritis Center Medical Group — Santa Monica
- Inland Rheumatology and Osteoporosis Medical Group, Inc — Upland
Florida
- San Marcus Research Clinic, Inc. — Hialeah
- Suncoast Clinical Research, Inc. — New Port Richey
- Suncoast Clinical Research — New Port Richey
- The Arthritis Center — Palm Harbor
Alabama
- Pinnacle Research Group — Anniston
- Achieve Clinical Research — Birmingham
Arizona
- Advanced Arthritis Care and Research — Scottsdale
Nevada
- Office of George Timothy Kelly, MD — Las Vegas
North Carolina
- PMG Research of Salisbury — Salisbury
Oklahoma
- Health Research of Oklahoma — Oklahoma City
Pennsylvania
- Altoona Center for Clinical Research — Duncansville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 31 participants |
| Start Date | 2015-04 |
| Est. Completion | 2016-06 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02387762
The ClinicalTrials.gov registry entry for NCT02387762 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 31 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Acerta Pharma, which has 17 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02387762 reports 17 study locations spanning 10 distinct geographic areas — top geographies include California, Florida, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02387762 about?
NCT02387762 is a clinical study titled "ACP-196 Versus Placebo in Subjects With Rheumatoid Arthritis on Background Methotrexate". This study is evaluating the safety, pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of ACP-196 in subjects with Rheumatoid Arthritis on background Methotrexate.
What is the current status of trial NCT02387762?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 31 participants. The study started on 2015-04. Estimated completion is 2016-06.
What conditions does trial NCT02387762 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02387762?
The interventions under investigation include: Placebo (DRUG), acalabrutinib (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02387762?
This trial is sponsored by Acerta Pharma, which has 17 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02387762 being conducted?
This trial has 17 study locations across Alabama, Arizona, California, Florida, Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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