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NCT07276581 · ClinicalTrials.gov registry record · Phase 2
A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis
A Phase 2 study of Rheumatoid Arthritis, sponsored by AstraZeneca.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 320
- Enrollment target
- 20
- Study locations
NCT07276581: Recruiting Phase 2 study of Rheumatoid Arthritis, sponsored by AstraZeneca.
NCT07276581 is a Phase 2 study of Rheumatoid Arthritis that is actively recruiting participants, run by AstraZeneca. The registered enrollment target is 320 participants, below the 4,689-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (93% lower). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07276581, a Phase 2 study of Rheumatoid Arthritis, is actively recruiting participants, sponsored by AstraZeneca.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 320 participants
- Enrollment target
- 20
- Study locations
Study Summary
Phase II study in participants with moderately-to-severely active rheumatoid Arthritis (RA) to evaluate efficacy and safety of AZD1163.
Primary Outcome
Change from baseline in DAS28-CRP at Week 12.
Conditions Studied
Interventions
- OTHER Placebo
- DRUG AZD1163
Study Locations (20)
Texas
- Research Site - Austin
- Research Site - Baytown
- Research Site - Houston
- Research Site - Houston
- Research Site - Mesquite
- Research Site - Tomball
Florida
- Research Site - Boynton Beach
- Research Site - Jacksonville
- Research Site - South Miami
- Research Site - Tampa
Arizona
- Research Site - Glendale
- Research Site - Prescott Valley
California
- Research Site - La Jolla
- Research Site - San Dimas
Illinois
- Research Site - Willowbrook
Louisiana
- Research Site - Lake Charles
Maryland
- Research Site - Baltimore
Massachusetts
- Research Site - New Bedford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 320 participants |
| Start Date | 2025-12-15 |
| Est. Completion | 2028-08-18 |
| Phase | Phase 2 |
What NCT07276581 shows while recruiting
NCT07276581 is an interventional study that assigns participants to a tested intervention. The registered 320 participants enrollment target is mid-sized for trials with a published cap, below the 4,689-participant average among 197 other Rheumatoid Arthritis trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Rheumatoid Arthritis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT07276581 names 20 study sites across 10 states, led by Texas, Florida, Arizona.
Frequently Asked Questions
What is clinical trial NCT07276581 about?
NCT07276581 is a clinical study titled "A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis". Phase II study in participants with moderately-to-severely active rheumatoid Arthritis (RA) to evaluate efficacy and safety of AZD1163.
What is the current status of trial NCT07276581?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 320 participants. The study started on 2025-12-15. Estimated completion is 2028-08-18.
What conditions does trial NCT07276581 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis.
What interventions are being tested in trial NCT07276581?
The interventions under investigation include: Placebo (OTHER), AZD1163 (DRUG).
Who is sponsoring clinical trial NCT07276581?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07276581 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Illinois, Louisiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Rheumatoid Arthritis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07276581's enrollment target sits among peer trials
320 56th of 197 higher than 142 of 197 other Rheumatoid Arthritis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rheumatoid Arthritis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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