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NCT02821741 · ClinicalTrials.gov registry record · NA
Effects of External Ear Stimulation on Pain Perception and Mood
A NA study of Pain in Healthy Participants, sponsored by National Center for Complementary and Integrative Health (NCCIH).
- Recruiting
- Registry status
- NA
- Development phase
- 76
- Enrollment target
- 1
- Study location
NCT02821741 is a NA study of Pain in Healthy Participants that is actively recruiting participants, run by National Center for Complementary and Integrative Health (NCCIH). The registered enrollment target is 76 participants. The trial reports 1 study location across 1 state.
The verdict
NCT02821741, a NA study of Pain in Healthy Participants, is actively recruiting participants, sponsored by National Center for Complementary and Integrative Health (NCCIH).
- RECRUITING
- Registry status
- NA
- Development phase
- 76 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: The vagus nerve runs from the brain to many organs. Stimulating it can affect the experience of pain. The nerve can be stimulated on the surface of the left ear. Researchers want to study how this stimulation affects the perception of pain. They also want to study how mood affects the experience of pain. Objective: To study the effects of mood and vagus nerve stimulation on the experience of pain. Eligibility: Healthy people ages 18 and older who are fluent in English Design: Participants will be pre-screened with a 15-minute phone call. Participants will have three 2-hour visits. At the screening visit, participants will be screened with: Medical and psychiatric history Physical and psychological exams Questionnaires about physical and psychiatric health and mood Urine tests A heat probe on the forearm. The temperature will be increased until it is painful but tolerable. Participants will have 2 testing sessions within 7 days. Before the testing, they cannot do the following: Eat, use nicotine, or exercise for at least 2 hours Drink alcohol for 24 hours Take certain medicines for 3 days Testing includes: Urine drug screening Left ear stimulation: In one session, the vagus nerve will be stimulated. In the other, an area of the ear away from the vagus nerve will be stimulated. This will be done with mild electric shocks that cause a tingling, pricking, or itchy feeling. Heat applied to the forearm until it is painful but tolerable Completing several forms on a computer or on paper about how they are feeling Monitors on the chest and a finger clip to monitor heart, breathing, and blood pressure
Conditions Studied
Interventions
- DEVICE The Twin Stim Plus, 3rd Edition
- DEVICE Medoc Pathway System
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 76 participants |
| Start Date | 2016-10-18 |
| Est. Completion | 2026-03-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02821741
The ClinicalTrials.gov registry entry for NCT02821741 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 76 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Center for Complementary and Integrative Health (NCCIH), which has 203 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Pain in Healthy Participants appearing as the primary indexed condition, and to 2 interventions - of which The Twin Stim Plus, 3rd Edition is the first listed.
NCT02821741 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT02821741 about?
NCT02821741 is a clinical study titled "Effects of External Ear Stimulation on Pain Perception and Mood". Background: The vagus nerve runs from the brain to many organs. Stimulating it can affect the experience of pain. The nerve can be stimulated on the surface of the left ear. Researchers want to study how this stimulation affects the perception of pain. They also want to study how mood affects the e...
What is the current status of trial NCT02821741?
This trial is currently recruiting. It is a NA study. The enrollment target is 76 participants. The study started on 2016-10-18. Estimated completion is 2026-03-30.
What conditions does trial NCT02821741 study?
This clinical trial studies the following conditions: Pain in Healthy Participants.
What interventions are being tested in trial NCT02821741?
The interventions under investigation include: The Twin Stim Plus, 3rd Edition (DEVICE), Medoc Pathway System (DEVICE).
Who is sponsoring clinical trial NCT02821741?
This trial is sponsored by National Center for Complementary and Integrative Health (NCCIH), which has 203 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02821741 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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