Wake Forest University Health Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Wake Forest University Health Sciences sits in the top decile of US sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count).

1,140 total trials 174 currently recruiting 724 completed early-phase tilt top decile by trial count

Wake Forest University Health Sciences: 1,140 sponsored US clinical trials, 174 recruiting.

Wake Forest University Health Sciences sponsors 1,140 registered US clinical trials on ClinicalTrials.gov, 174 of them currently recruiting, and 724 completed. 111 of these trials are in Phase 3-4 (later-stage) and 239 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 9 trials.

Top-decile sponsor footprint

Wake Forest University Health Sciences ranks in the top decile of sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

724 of 885 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,140 total, page 9 of 23

COMPLETED

Psychometric Properties of the SMART Feeding Tool

NCT05729828

TERMINATED

Radiation Therapy on Pelvic Floor Disorders in Women

NCT04623515

COMPLETED NA

Integrated Intervention for Caregivers--Pilot RCT

NCT03487627

COMPLETED NA

Suture Closure AFtEr VEIN Access for Cardiac Procedures (SAFE-VEIN) Trial

NCT04632641

COMPLETED Early Phase 1

Muscadine Grape Extract to Improve Fatigue

NCT04495751

COMPLETED Phase 2

Rosacea and Ivermectin

NCT04275999

COMPLETED NA

LOVE Trial: Limits On Vaginal Intercourse After Mid-urEthral Sling

NCT04680897

TERMINATED NA

Exercise as Adjunctive Treatment for Refractory Epilepsy

NCT04607317

COMPLETED

Preop COVID Testing Patterns

NCT04838119

COMPLETED NA

Wake Forest Post-ICU Telehealth (WFIT) Program

NCT04576065

TERMINATED

User Experience of the OSR M-1

NCT04733677

TERMINATED NA

Cancer Within a Pandemic: A Telemental Health Intervention

NCT04659993

COMPLETED NA

SMS System for Patients With Uncontrolled Hypertension

NCT03596242

TERMINATED Phase 4

Safety and Outcomes Associated With Continuous Versus Intermittent Infusion Vancomycin

NCT04648696

COMPLETED Phase 2

Quad Shot Radiotherapy in Combination With Immune Checkpoint Inhibition

NCT04454489

COMPLETED NA

PEMF Therapy to Treat Interstitial Cystitis/Bladder Pain Syndrome

NCT04540887

COMPLETED Phase 4

Pain Response Evaluation of a Combined Intervention to Cope Effectively

NCT04395001

COMPLETED NA

Use of a Digitally Enabled App With Clinical Team Interface in the Management of Depression

NCT04891224

COMPLETED Phase 2

Hidradenitis Suppurativa Wound Care

NCT04354012

COMPLETED NA

Pharmacogenomic-Guided Supportive Care in Hematopoietic Cell Transplantation

NCT04727827

COMPLETED

Application to Improve Patient Engagement and Decrease Postoperative Opioid Consumption in Patients for Colorectal Surgery

NCT06350916

TERMINATED Phase 2

Solriamfetol in Improving Sleep in Patients With Grade II-IV Glioma

NCT03868943

TERMINATED Phase 2

Study Of Intrabucally Administered Electromagnetic Fields and Regorafenib

NCT04327700

COMPLETED NA

Telephone-Based Intervention to Treat Depression and Anxiety in Hispanic Cancer Survivors

NCT04430335

COMPLETED

RUral dispaRities in prehospitAL STEMI

NCT04381260

COMPLETED NA

Fractional Ablative Laser Treatment for Skin Grafts

NCT04176705

COMPLETED NA

A Device to Determine Return of Sensation From Spinal Block

NCT04553913

COMPLETED NA

Pharmacogenomic Testing to Personalize Supportive Oncology

NCT04500301

TERMINATED

Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only

NCT04527523

TERMINATED NA

Effect of Fish Oil on Athlete's Executive Function

NCT04570995

COMPLETED NA

Increased Monitoring of Physical Activity and Calories With Technology

NCT03961061

TERMINATED Phase 2

Generate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic Effects

NCT04431206

COMPLETED NA

Impact Of Nurse Navigation Program on Outcomes in Patients With GI Cancers

NCT04602611

COMPLETED NA

Promoting Altruism to Enhance Vaccine Acceptance

NCT04568590

COMPLETED

Extubation Criteria in Patients Greater Than 59 Years of Age

NCT04596735

TERMINATED Phase 2

Study of Hypofractionated Radiotherapy Alone in Locally Advanced Nonsmall Cell Lung Cancer Patients

NCT04398199

COMPLETED

COVID-19 Amyotrophic Lateral Sclerosis (ALS) Registry

NCT04559009

COMPLETED

ABTHERA ADVANCE™ Use Without Wittman Patch

NCT04986943

COMPLETED NA

A Pilot Trial of Continuous Portable Postoperative Hemodynamic And Saturation Monitoring On Hospital Wards

NCT04574908

COMPLETED NA

Assessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among Survivors

NCT03935282

COMPLETED NA

CONNECTing Head and Neck Caregivers to Supportive Care Resources

NCT03875885

TERMINATED Phase 2

CPI-613 in Combination With Bendamustine in Patients With Relapsed/Refractory T-Cell Non-Hodgkin Lymphoma

NCT04217317

TERMINATED Phase 2

Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain

NCT04356352

COMPLETED NA

Shared Healthcare Actions and Reflections Electronic Systems in Survivorship

NCT04337203

COMPLETED NA

Dance and Diabetes/Prediabetes Self-Management

NCT04427982

COMPLETED

COVID-19 IgG Formation in Physicians at ALGH and Their Household Members

NCT04540484

COMPLETED NA

Effect of Theta Burst Stimulation on Alcohol Cue Reactivity

NCT04223154

COMPLETED NA

Incentives to Decrease Opioid Use - Pilot

NCT04235582

COMPLETED NA

QuitFast: Evaluating Transcranial Magnetic Stimulation as a Tool to Reduce Smoking Directly Following a Quit Attempt

NCT04159571

TERMINATED Phase 1

Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities

NCT04037527

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Phase Distribution

PhaseTrial count
Phase 1 96
Phase 2 143
Phase 3 31
Phase 4 80

What is open in the Wake Forest University Health Sciences pipeline

174 recruiting of 1,140 indexed (15% open); 724 completed (64%).

Phase mix: 111 late (III/IV) vs 239 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Wake Forest University Health Sciences: open-pipeline peers nationwide

Peers matched on 1,140 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share Wake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthUniversity of North Carolina, Chapel HillUniversity of FloridaBaylor UniversityCornell UniversityArrowhead Regional Medical CenterAurinia Pharmaceuticals
Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,140 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Wake Forest University Health Sciences page

1,140 registered trials is a research-attention snapshot, not an endorsement of Wake Forest University Health Sciences or any single study.

  • 174 of Wake Forest University Health Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Wake Forest University Health Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Wake Forest University Health Sciences pipeline card: 1,140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.