Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04381260 · ClinicalTrials.gov registry record

RUral dispaRities in prehospitAL STEMI

A clinical trial, sponsored by Wake Forest University Health Sciences.

Completed
Registry status
473
Enrollment target

NCT04381260: Completed study, sponsored by Wake Forest University Health Sciences.

NCT04381260 is a clinical trial that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 473 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04381260 has completed, sponsored by Wake Forest University Health Sciences.

COMPLETED
Registry status
473 participants
Enrollment target

Study Summary

Rural Americans are more likely to be unhealthy, older, living in poverty, uninsured, and medically underserved. The CDC has made achieving health equity and improving cardiovascular health for rural Americans one of their Healthy People 2020 overarching goals. ST-Elevation Myocardial Infarction (STEMI) is a life-threatening cardiovascular emergency that frequently affects people without warning within the communities the Participants live and work. Patients with STEMI have a linear relationship between first medical contact to Percutaneous Coronary Intervention (PCI) time and mortality. Delays are particularly important in STEMI patients with cardiogenic shock, who experience an excess 3.3 deaths per 100 for every 10 minute delay to PCI (for PCI times between 60-180 minutes). Delayed PCI is also associated with a higher rate of long term morbidity, including congestive heart failure and repeat MI. Unfortunately, many rural EMS agencies fail to consistently achieve the recommended 90 minute PCI time goal. Rural agencies are less likely than urban/suburban agencies to meet time goals and this disparity exposes rural patients to excess morbidity and mortality. The American College of Cardiology/American Heart Association (ACC/AHA) endorse the need for prehospital strategies to reduce total ischemic time, particularly in rural settings.

Primary Outcome

Aim 1 will be accomplished by developing a 2016-2019 STEMI data registry, which will be utilized to identify high- and low-performing rural EMS agencies. After identifying these agencies, Key Informants will participate in interviews designed to assess facilitators and barriers to achieving STEMI time metrics.

Interventions

  • OTHER No intervention
  • OTHER Interview
  • OTHER Survey

Trial Details

FieldValue
Enrollment Target 473 participants
Start Date 2020-12-15
Est. Completion 2022-06-02
Wake Forest University Health Sciences

1,140 total trials

What the finished NCT04381260 record still lists

NCT04381260 is an observational study that tracks outcomes without assigning an intervention. The registered 473 participants enrollment target is mid-sized for trials with a published cap.

The record links to 0 conditions, and to 3 interventions - of which No intervention is the first listed.

NCT04381260 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT04381260 about?

NCT04381260 is a clinical study titled "RUral dispaRities in prehospitAL STEMI". Rural Americans are more likely to be unhealthy, older, living in poverty, uninsured, and medically underserved. The CDC has made achieving health equity and improving cardiovascular health for rural Americans one of their Healthy People 2020 overarching goals. ST-Elevation Myocardial Infarction (ST...

What is the current status of trial NCT04381260?

This trial is currently completed. The enrollment target is 473 participants. The study started on 2020-12-15. Estimated completion is 2022-06-02.

What interventions are being tested in trial NCT04381260?

The interventions under investigation include: No intervention (OTHER), Interview (OTHER), Survey (OTHER).

Who is sponsoring clinical trial NCT04381260?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT05624996 · 474 participants · Phase 3

    Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

  • NCT06051695 · 474 participants · Phase 1

    A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

  • NCT06632977 · 474 participants · Phase 2

    Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

  • NCT06375083 · 472 participants · Phase 2

    Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04381260, the US trial registry maintained by the National Library of Medicine. NCT04381260 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.