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NCT04356352 · ClinicalTrials.gov registry record · Phase 2
Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain
A Phase 2 study, sponsored by Wake Forest University Health Sciences.
- Terminated
- Registry status
- Phase 2
- Development phase
- 33
- Enrollment target
NCT04356352: Clinical Trial Phase 2 study, sponsored by Wake Forest University Health Sciences.
NCT04356352 is a Phase 2 study that was terminated before completion, run by Wake Forest University Health Sciences. The registered enrollment target is 33 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04356352, a Phase 2 study, was terminated before completion, sponsored by Wake Forest University Health Sciences.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 33 participants
- Enrollment target
Study Summary
The primary hypothesis is that esmolol and lidocaine, when given without the use of a tourniquet, provide relief of propofol injection pain that is superior to placebo when assessed using the propofol pain scoring tool
Primary Outcome
pain scoring system previously used by studies looking at various remedies to decrease Propofol injection pain - 0-10 with 0=no pain up to 10=worst pain imaginable
Interventions
- OTHER Placebo
- DRUG Lidocaine
- DRUG Esmolol
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2020-09-09 |
| Est. Completion | 2023-08-25 |
| Phase | Phase 2 |
Why NCT04356352 stopped before completion
NCT04356352 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT04356352 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04356352 about?
NCT04356352 is a clinical study titled "Lidocaine, Esmolol, or Placebo to Relieve IV Propofol Pain". The primary hypothesis is that esmolol and lidocaine, when given without the use of a tourniquet, provide relief of propofol injection pain that is superior to placebo when assessed using the propofol pain scoring tool
What is the current status of trial NCT04356352?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 33 participants. The study started on 2020-09-09. Estimated completion is 2023-08-25.
What interventions are being tested in trial NCT04356352?
The interventions under investigation include: Placebo (OTHER), Lidocaine (DRUG), Esmolol (DRUG).
Who is sponsoring clinical trial NCT04356352?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04356352's enrollment target sits among peer trials
33 1553rd of 2000 higher than 438 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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