Wake Forest University Health Sciences

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Wake Forest University Health Sciences sits in the top decile of US sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count).

1,140 total trials 174 currently recruiting 724 completed early-phase tilt top decile by trial count

Wake Forest University Health Sciences: 1,140 sponsored US clinical trials, 174 recruiting.

Wake Forest University Health Sciences sponsors 1,140 registered US clinical trials on ClinicalTrials.gov, 174 of them currently recruiting, and 724 completed. 111 of these trials are in Phase 3-4 (later-stage) and 239 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 9 trials.

Top-decile sponsor footprint

Wake Forest University Health Sciences ranks in the top decile of sponsors by registered trial count (#27 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 44/100

724 of 885 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (81.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,140 total, page 4 of 23

RECRUITING NA

Experimental Round Spermatid Injection (ROSI) to Treat Infertile Couples

NCT04298255

RECRUITING NA

Effects of Systematic Cervical Exam Training on Labor and Delivery Care

NCT04421768

RECRUITING Phase 2

Pilot Study of Performance Status 2 vs. Performance Status 0-1 Non-small Cell Lung Cancer Patients Treated With Chemo/Immunotherapy

NCT04253964

RECRUITING Phase 2

Cetuximab After Immunotherapy for the Treatment of Head and Neck Squamous Cell Cancer

NCT04375384

RECRUITING NA

Prospective Measurement of Normal Venous Sinus Pressures

NCT03948971

RECRUITING

Pelvic and Acetabular Fracture: A Prospective Observational Study

NCT04615104

RECRUITING

Self Reported Pain in Women While Undergoing Treatment for Non-metastatic Breast Cancer

NCT04174742

RECRUITING NA

Muscle Fiber Fragments for Improved Function of Rotator Cuff Musculature Following Rotator Cuff Repair

NCT03752034

RECRUITING

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

NCT03998202

RECRUITING

Novel 3D Hematological Malignancy Organoid to Study Disease Biology and Chemosensitivity

NCT03890614

RECRUITING NA

Cereset Research Exploratory Study

NCT03777267

RECRUITING

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

NCT03615235

RECRUITING NA

Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy

NCT03716167

RECRUITING NA

Brain Energy for Amyloid Transformation in Alzheimer's Disease Study

NCT03472664

RECRUITING

Factors Affecting Post-transplant Cyclophosphamide (PTCy) Efficacy

NCT03555851

RECRUITING Phase 4

Improving Pain Control in Paraesophageal Hernia Repair: Intravenous Lidocaine Versus Placebo

NCT04096170

RECRUITING Phase 4

Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study

NCT04207931

RECRUITING

Reliability of Pupil Response to Acute Pain

NCT02628314

RECRUITING

Use of an Integrated Orthotic and Rehabilitation Initiative for Treatment of Lower Extremity Musculoskeletal Disorders

NCT05780502

RECRUITING Phase 2

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

NCT02422641

RECRUITING

Wake Forest Alzheimer's Disease Clinical Core

NCT03140865

RECRUITING

Facial Analysis to Classify Difficult Intubation

NCT01612949

RECRUITING

Collection and Storage of Tissue Samples From Patients Undergoing Surgery For Suspected Solid Tumors

NCT00900471

RECRUITING

The Prospective Collection, Storage and Reporting of Data on Patients Undergoing Hematopoietic Stem Cell Transplantation Utilizing a Standard Preparative Regimen

NCT01890486

ACTIVE NOT RECRUITING Phase 4

GLP-1s to Enhance Lasting Optimal Weight

NCT06861439

ACTIVE NOT RECRUITING

Assessing Chest Pain Using Point-of-Care High-Sensitivity Troponin I in the Emergency Department

NCT06899776

ACTIVE NOT RECRUITING NA

Telehealth-Enhanced Assessment and Management

NCT06247254

ACTIVE NOT RECRUITING NA

A Web-based Program to Help Caregivers of Lung Patients Learn About Available Supportive Care Resources

NCT06383988

ACTIVE NOT RECRUITING NA

Evaluating a Physical Activity Index for Assessment and Counseling for Breast and Colon Cancer Survivors

NCT06340503

ACTIVE NOT RECRUITING Early Phase 1

Azelaic Acid as a Novel Treatment for Central Centrifugal Cicatricial Alopecia (CCCA)

NCT05416333

ACTIVE NOT RECRUITING NA

Calcium Carbonate on Labor Induction

NCT06352775

ACTIVE NOT RECRUITING NA

Developing an Internet-Delivered Sexual Health Program for Breast Cancer Survivors, SHINE Trial

NCT06216574

ACTIVE NOT RECRUITING NA

The Bennett Kids PowerUP Project

NCT05858580

ACTIVE NOT RECRUITING Early Phase 1

Experience With Topical Acne Treatment

NCT05582434

ACTIVE NOT RECRUITING Phase 4

Preference of Women With Recurrent Urinary Tract Infection for Vaginal Estradiol Tablet vs Cream

NCT05723601

ACTIVE NOT RECRUITING Phase 2

Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer

NCT06027268

ACTIVE NOT RECRUITING NA

Deucravacitinib Adherence Study

NCT05570955

ACTIVE NOT RECRUITING NA

Barbed-suture Efficiency Study for Sacrocolpopexy

NCT05760794

ACTIVE NOT RECRUITING NA

Contingency Management for Drug Use: Does Age Matter?

NCT05521854

ACTIVE NOT RECRUITING NA

Effects of Dance and Music Appreciation on Brain Health and Fitness in People at Risk for Alzheimer's Disease

NCT05507905

ACTIVE NOT RECRUITING

Immune Signature Analysis of Disease Progression in Post Immunotherapy Lung Cancer Patients

NCT05415358

ACTIVE NOT RECRUITING

Prospective Evaluation of Intrathecal Targeted Drug Delivery for Cancer Associated Pain

NCT05674240

ACTIVE NOT RECRUITING NA

The Arteriovenous Vascular (AV) ACCESS Trial

NCT04646226

ACTIVE NOT RECRUITING Phase 4

Long-term Effectiveness of the Antiobesity Medication Phentermine

NCT05176626

ACTIVE NOT RECRUITING NA

Primary Care Implementation and Evaluation of Coach McLungs

NCT05059210

ACTIVE NOT RECRUITING Phase 2

Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction

NCT05093959

ACTIVE NOT RECRUITING NA

Implementation and Effectiveness Trial of HN-STAR

NCT04208490

ACTIVE NOT RECRUITING

Enhancing Rural Health Via Cardiovascular Telehealth for Rural Patients Implementation (E-VICTORS)

NCT04617834

ACTIVE NOT RECRUITING NA

Xerosis and Use of Topical Moisturizer

NCT04341623

ACTIVE NOT RECRUITING

FNS (FEMORAL NECK SYSTEM) Study

NCT04577261

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Phase Distribution

PhaseTrial count
Phase 1 96
Phase 2 143
Phase 3 31
Phase 4 80

What is open in the Wake Forest University Health Sciences pipeline

174 recruiting of 1,140 indexed (15% open); 724 completed (64%).

Phase mix: 111 late (III/IV) vs 239 early (I/II) (early-phase heavy).

Top condition: Breast Cancer (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Wake Forest University Health Sciences: open-pipeline peers nationwide

Peers matched on 1,140 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share Wake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthUniversity of North Carolina, Chapel HillUniversity of FloridaBaylor UniversityCornell UniversityArrowhead Regional Medical CenterAurinia Pharmaceuticals
Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Wake Forest University Health Sciences sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,140 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Wake Forest University Health Sciences page

1,140 registered trials is a research-attention snapshot, not an endorsement of Wake Forest University Health Sciences or any single study.

  • 174 of Wake Forest University Health Sciences's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Breast Cancer is the condition Wake Forest University Health Sciences studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Breast Cancer trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Wake Forest University Health Sciences pipeline card: 1,140 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.