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NCT05582434 · ClinicalTrials.gov registry record · Early Phase 1
Experience With Topical Acne Treatment
A Early Phase 1 study of Acne, sponsored by Wake Forest University Health Sciences.
- Active
- Registry status
- Early Phase 1
- Development phase
- 72
- Enrollment target
- 1
- Study location
NCT05582434: Active Early Phase 1 study of Acne, sponsored by Wake Forest University Health Sciences.
NCT05582434 is a Early Phase 1 study of Acne that is active but no longer recruiting, run by Wake Forest University Health Sciences. The registered enrollment target is 72 participants, below the 140-participant average among 26 other Acne trials with a reported enrollment target (49% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05582434, a Early Phase 1 study of Acne, is active but no longer recruiting, sponsored by Wake Forest University Health Sciences.
- ACTIVE NOT RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 72 participants
- Enrollment target
- 1
- Study location
Study Summary
Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using topical medications.1 Nonadherence can result in multiple negative effects including treatment failure, increased healthcare costs, and decreased quality of life. Primary nonadherence refers to problems acquiring and starting treatment. Challenges to this form of nonadherence include a lack of knowledge, misunderstanding of usage, poor communication with provider, increased cost, and fear of side effects.2 Secondary nonadherence refers to when the patient does not use the medication as prescribed. Hurdles to secondary nonadherence include delayed results, increased complexity of treatment plan, adverse effects, busy lifestyle, and inconvenience.2
Primary Outcome
Medication adherence measured by recording the weight of medication (in milligrams) in the bottle with electronic monitor attached
Conditions Studied
Interventions
- DRUG clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel
- DRUG adapalene 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gel
- DRUG Compounded BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gel
Study Locations (1)
North Carolina
- Wake Forest University Health Sciences - Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 72 participants |
| Start Date | 2024-02-15 |
| Est. Completion | 2026-11 |
| Phase | Early Phase 1 |
What the registry record for NCT05582434 still lists
NCT05582434 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 72 participants, a relatively small participant target, below the 140-participant average among 26 other Acne trials with a reported enrollment target (49% lower).
The record links to 1 condition, with Acne appearing as the primary indexed condition, and to 3 interventions - of which clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel is the first listed.
NCT05582434 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT05582434 about?
NCT05582434 is a clinical study titled "Experience With Topical Acne Treatment". Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using topical medications.1 Nonadherence can result in multiple negative effects...
What is the current status of trial NCT05582434?
This trial is currently active not recruiting. It is a Early Phase 1 study. The enrollment target is 72 participants. The study started on 2024-02-15. Estimated completion is 2026-11.
What conditions does trial NCT05582434 study?
This clinical trial studies the following conditions: Acne.
What interventions are being tested in trial NCT05582434?
The interventions under investigation include: clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel (DRUG), adapalene 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gel (DRUG), Compounded BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gel (DRUG).
Who is sponsoring clinical trial NCT05582434?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05582434 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05582434's enrollment target sits among peer trials
72 14th of 26 higher than 13 of 26 other Acne trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Acne trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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