Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT02991404 · ClinicalTrials.gov registry record · Early Phase 1

Single Injection Adductor Canal Block Versus Continuous Adductor Canal Infusion for Total Knee Arthroplasty

A Early Phase 1 study of Pain, Postoperative and Total Knee Arthroplasty, sponsored by Wake Forest University Health Sciences.

Completed
Registry status
Early Phase 1
Development phase
60
Enrollment target
1
Study location

NCT02991404: Completed Early Phase 1 study of Pain, Postoperative and Total Knee Arthroplasty, sponsored by Wake Forest University Health Sciences.

NCT02991404 is a Early Phase 1 study of Pain, Postoperative and Total Knee Arthroplasty that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 60 participants, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT02991404, a Early Phase 1 study of Pain, Postoperative and Total Knee Arthroplasty, has completed, sponsored by Wake Forest University Health Sciences.

COMPLETED
Registry status
Early Phase 1
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

Patients undergoing Primary Total Knee Arthroplasty will be randomized to receive either multimodal single injection adductor canal block with sham infusion catheter or continuous infusion of local anesthetic (control) for postoperative analgesia. Primary end point is pain scores at 30 hours post performance of block procedure.

Primary Outcome

At 30 hours pain scores between the two groups will be compared for determining statistically significant differences

Interventions

  • PROCEDURE Multimodal Peripheral Nerve Block Injection
  • PROCEDURE Single Shot Adductor Canal Block
  • DRUG Initial Bolus
  • DRUG Continuous infusion

Study Locations (1)

North Carolina

  • Wake Forest Baptist Hospital - Winston-Salem

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2017-02-17
Est. Completion 2017-11-15
Phase Early Phase 1
Wake Forest University Health Sciences

1,140 total trials

What the finished NCT02991404 record still lists

NCT02991404 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 272-participant average among 113 other Pain, Postoperative trials with a reported enrollment target (78% lower).

The record links to 3 conditions, with Pain, Postoperative appearing as the primary indexed condition, and to 4 interventions - of which Multimodal Peripheral Nerve Block Injection is the first listed.

NCT02991404 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT02991404 about?

NCT02991404 is a clinical study titled "Single Injection Adductor Canal Block Versus Continuous Adductor Canal Infusion for Total Knee Arthroplasty". Patients undergoing Primary Total Knee Arthroplasty will be randomized to receive either multimodal single injection adductor canal block with sham infusion catheter or continuous infusion of local anesthetic (control) for postoperative analgesia. Primary end point is pain scores at 30 hours post p...

What is the current status of trial NCT02991404?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 60 participants. The study started on 2017-02-17. Estimated completion is 2017-11-15.

What conditions does trial NCT02991404 study?

This clinical trial studies the following conditions: Pain, Postoperative, Total Knee Arthroplasty, Adductor Canal Block.

What interventions are being tested in trial NCT02991404?

The interventions under investigation include: Multimodal Peripheral Nerve Block Injection (PROCEDURE), Single Shot Adductor Canal Block (PROCEDURE), Initial Bolus (DRUG), Continuous infusion (DRUG).

Who is sponsoring clinical trial NCT02991404?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02991404 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pain, Postoperative

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02991404's enrollment target sits among peer trials

60 79th of 113 higher than 30 of 113 other Pain, Postoperative trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pain, Postoperative trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00576069 · 60 participants

    Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma

  • NCT01297400 · 60 participants · Phase 2

    Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

  • NCT01734122 · 60 participants

    Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

  • NCT01804634 · 60 participants · Phase 2

    Reduced Intensity Haploidentical BMT for High Risk Solid Tumors

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT02991404, the US trial registry maintained by the National Library of Medicine. NCT02991404 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.