University of North Carolina, Chapel Hill

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, University of North Carolina, Chapel Hill sits in the top decile of US sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count).

1,109 total trials 108 currently recruiting 881 completed early-phase tilt top decile by trial count

University of North Carolina, Chapel Hill: 1,109 sponsored US clinical trials, 108 recruiting.

University of North Carolina, Chapel Hill sponsors 1,109 registered US clinical trials on ClinicalTrials.gov, 108 of them currently recruiting, and 881 completed. 69 of these trials are in Phase 3-4 (later-stage) and 203 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Obesity, with 17 trials.

Top-decile sponsor footprint

University of North Carolina, Chapel Hill ranks in the top decile of sponsors by registered trial count (#28 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

881 of 962 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.6%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,109 total, page 22 of 23

COMPLETED NA

C2P Mobilization Intervention (Pilot)

NCT00393575

COMPLETED Phase 2

Study of Aripiprazole to Treat Children and Adolescents With Autism

NCT00619190

TERMINATED Phase 3

Comparison of Low-dose Epidural With Intravenous Narcotic Versus Intravenous Narcotic Alone

NCT00287326

COMPLETED NA

Efficacy of Probiotic Bacteria in Subjects With IBS or Functional Diarrhea/ Bloating

NCT00618904

COMPLETED NA

Family-based HIV Prevention for Adolescent Girls

NCT00243126

COMPLETED

Hepatitis B Vaccine Genetics: A Substudy of ATN 024 and ATN 025

NCT00142740

COMPLETED NA

Daily Vitamin K in Patients on Warfarin With Unstable INRs

NCT00287313

COMPLETED Phase 1

Inhalation of 20,000 Endotoxin Units(EU) of Clinical Center Reference Endotoxin in Healthy Volunteers

NCT00654134

COMPLETED Phase 4

The Utility of Nexium in Chronic Cough and Reflux Disease

NCT00287339

COMPLETED

Surgical Decision Making Among People With Inflammatory Bowel Disease

NCT00438711

TERMINATED

Development of a Life Skills Intervention for Young Adolescents Perinatally-Infected With HIV and Their Caregivers

NCT00224900

COMPLETED Phase 4

Immunologic Memory (Supp. of ATN 024)

NCT00142753

COMPLETED Phase 1

The Role of Vitamins E and C in Maintaining Lung Health in People With Asthma

NCT00142610

COMPLETED Phase 2

Early Intervention With Fluoxetine in Autism

NCT00183339

COMPLETED Phase 1

Study of Amantadine for Weight Stabilization During Olanzapine Treatment

NCT00287352

COMPLETED Phase 2

Efficacy and Tolerability of Baclofen for Alcohol Dependence

NCT00877734

COMPLETED NA

Healthy Choices to Promote Health and Reduce Risk in HIV-Infected Youth

NCT00103532

COMPLETED NA

North Carolina WISEWOMAN: Weight-Wise Pilot Study

NCT00288301

COMPLETED NA

Adolescent Safer Sex Social Network Intervention

NCT00107562

COMPLETED Phase 2

Acupuncture for the Prevention of Postdates Pregnancy

NCT00312585

COMPLETED

Albumin Use in Burn Patients

NCT00609414

COMPLETED Phase 4

Treatment of Acute HIV With Emtricitabine, Tenofovir and Efavirenz (CID 0805)

NCT00924898

COMPLETED NA

Friendship Based HIV/STI (Sexually Transmitted Infections) Intervention for African American Females

NCT00109421

COMPLETED NA

EARLY IFNb-1a and Atorvastatin Combination Therapy of Isolated Clinical Syndrome Suggestive of Multiple Sclerosis

NCT00137176

COMPLETED NA

Preventing Falls Through Enhanced Pharmaceutical Care

NCT00618800

COMPLETED NA

A Couples Approach to Enhance Breast Cancer Survivorship

NCT00665899

COMPLETED

Typology of Adherence in Adolescents: Phase II

NCT00106678

COMPLETED Early Phase 1

Oral Peanut Immunotherapy for Peanut Allergic Patients

NCT01891136

COMPLETED

Early Brain Development in Twins

NCT01409746

COMPLETED NA

IV vs. IA tPA (Activase) in Acute Ischemic Stroke With CTA Evidence of Major Vessel Occlusion

NCT00624000

COMPLETED Phase 2

Effectiveness of Two Hepatitis B Vaccines in HIV-negative Youths

NCT00107042

COMPLETED NA

MOTOR: Maternal Oral Therapy to Reduce Obstetric Risk

NCT00097656

COMPLETED Phase 4

Comparison of Three Hepatitis B Vaccination Regimens in HIV-Positive Youth

NCT00106964

COMPLETED

Simplified Consent for HIV Vaccine Trials

NCT00105339

COMPLETED

Connect to Protect Partnerships for Youth Prevention Interventions: Phase II

NCT00103896

TERMINATED Phase 1

Response of Airway Cells to 20,000 EU of Endotoxin in Normal Adults

NCT00838851

COMPLETED

Metabolic Abnormalities in HIV Infected and Uninfected Young Women

NCT00067587

COMPLETED

Engaging Care for HIV-infected Adolescent Females.

NCT00489034

COMPLETED Phase 4

4-Day-A-Week Treatment Plan for HIV Infected Adolescents

NCT00068809

COMPLETED Phase 2

Reducing Symptoms of Depression in Low-Income Mothers

NCT00074789

COMPLETED NA

NC Enhanced WISEWOMAN Project

NCT00288327

COMPLETED

A Novel Method to Determine HIV Incidence Among Youth

NCT00103883

COMPLETED NA

Treatment of Egg Allergy in Children Through Oral Desensitization (EGG OIT)

NCT00597558

COMPLETED

Evaluation of Genetic Markers as Explanations for the Observed Differences in Disease Progression in HIV+ Youth

NCT00107029

COMPLETED Phase 2

Ziprasidone in Early Onset Schizophrenia Spectrum Disorders

NCT01006551

COMPLETED Phase 1

Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults

NCT00839189

COMPLETED

Prospective Studies of the Pathogenesis of Schizophrenia

NCT00877552

TERMINATED Phase 3

Carotid Occlusion Surgery Study

NCT00029146

COMPLETED NA

Genetic Susceptibility TO Ozone-induced Airway Inflammation in Humans

NCT00840528

COMPLETED Phase 4

Treatment of Early Onset Schizophrenia Spectrum Disorders (TEOSS)

NCT00053703

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Phase Distribution

PhaseTrial count
Phase 1 111
Phase 2 92
Phase 3 13
Phase 4 56

What is open in the University of North Carolina, Chapel Hill pipeline

108 recruiting of 1,109 indexed (10% open); 881 completed (79%).

Phase mix: 69 late (III/IV) vs 203 early (I/II) (early-phase heavy).

Top condition: Obesity (17 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

University of North Carolina, Chapel Hill: open-pipeline peers nationwide

Peers matched on 1,109 registered trials and 10% open enrollment, not the therapeutic-area sidebar.

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 8%10%12%14%16%18%20% Total trials Recruiting share University of North Carolina, Chapel HillUniversity of FloridaWake Forest University Health SciencesUniversity of Alabama at BirminghamNYU Langone HealthChildren's Hospitals and Clinics of MinnesotaCytokineticsSanofiOhio University
University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

University of North Carolina, Chapel Hill sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,109 trials (± recruiting share)

Sponsors near 10% open enrollment (± trial volume)

What to do with this University of North Carolina, Chapel Hill page

1,109 registered trials is a research-attention snapshot, not an endorsement of University of North Carolina, Chapel Hill or any single study.

  • 108 of University of North Carolina, Chapel Hill's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Obesity is the condition University of North Carolina, Chapel Hill studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Obesity trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. University of North Carolina, Chapel Hill pipeline card: 1,109 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.