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NCT00029146 · ClinicalTrials.gov registry record · Phase 3
Carotid Occlusion Surgery Study
A Phase 3 study, sponsored by University of North Carolina, Chapel Hill.
- Terminated
- Registry status
- Phase 3
- Development phase
- 700
- Enrollment target
NCT00029146: Clinical Trial Phase 3 study, sponsored by University of North Carolina, Chapel Hill.
NCT00029146 is a Phase 3 study that was terminated before completion, run by University of North Carolina, Chapel Hill. The registered enrollment target is 700 participants, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00029146, a Phase 3 study, was terminated before completion, sponsored by University of North Carolina, Chapel Hill.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 700 participants
- Enrollment target
Study Summary
The purpose of this study is to determine if extracranial-intracranial bypass surgery when added to best medical therapy can reduce the subsequent risk of ipsilateral stroke in high-risk patients with recently symptomatic carotid occlusion and increased cerebral oxygen extraction fraction measured by positron emission tomography (PET).
Primary Outcome
2 yr Kaplan-Meier estimates of the proportions.Proportions expressed as percentages for reporting purposes. Ipsilateral ischemic stroke is defined as the clinical diagnosis of a focal neurological deficit due to cerebral ischemia clinically localizable within the internal carotid artery territory distally to the symptomatic occluded internal carotid artery that lasts for more than 24 hours. All stroke is defined as the clinical diagnosis of a focal deficit due to ischemia or hemorrhage clinicall
Interventions
- PROCEDURE extracranial-intracranial bypass surgery
- DRUG best medical therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 700 participants |
| Start Date | 2002-07 |
| Est. Completion | 2010-06 |
| Phase | Phase 3 |
Why NCT00029146 stopped before completion
NCT00029146 is an interventional study that assigns participants to a tested intervention. The registered 700 participants enrollment target is mid-sized for trials with a published cap, roughly in line with the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target.
The record links to 0 conditions, and to 2 interventions - of which extracranial-intracranial bypass surgery is the first listed.
NCT00029146 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00029146 about?
NCT00029146 is a clinical study titled "Carotid Occlusion Surgery Study". The purpose of this study is to determine if extracranial-intracranial bypass surgery when added to best medical therapy can reduce the subsequent risk of ipsilateral stroke in high-risk patients with recently symptomatic carotid occlusion and increased cerebral oxygen extraction fraction measured b...
What is the current status of trial NCT00029146?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 700 participants. The study started on 2002-07. Estimated completion is 2010-06.
What interventions are being tested in trial NCT00029146?
The interventions under investigation include: extracranial-intracranial bypass surgery (PROCEDURE), best medical therapy (DRUG).
Who is sponsoring clinical trial NCT00029146?
This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT00029146's enrollment target sits among peer trials
700 506th of 2000 higher than 1,485 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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