Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00137176 · ClinicalTrials.gov registry record · NA

EARLY IFNb-1a and Atorvastatin Combination Therapy of Isolated Clinical Syndrome Suggestive of Multiple Sclerosis

A NA study of Multiple Sclerosis, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
NA
Development phase
30
Enrollment target
1
Study location

NCT00137176 is a NA study of Multiple Sclerosis that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 30 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00137176, a NA study of Multiple Sclerosis, has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The primary purpose is to determine the changes in gene expression induced by IFNb-1a (Rebif) and atorvastatin (Lipitor) combination therapy in patients with an isolated clinical syndrome suggestive of multiple sclerosis (MS), to identify markers of therapeutic response, and to predict patients' clinical response based on their in vitro response to this combination therapy measured by the gene expression levels in activated peripheral blood mononuclear cells (PBMCs).

Conditions Studied

Interventions

  • DRUG Rebif

Study Locations (1)

North Carolina

  • University of North Carolina-Chapel Hill MS Clinic Within the Neuroscience Hospital - Chapel Hill

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2004-10
Est. Completion 2008-10
Phase NA

What the Registry Record Tells You About NCT00137176

The ClinicalTrials.gov registry entry for NCT00137176 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (95% lower). The listed sponsor is University of North Carolina, Chapel Hill, which has 1,109 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which Rebif is the first listed.

NCT00137176 reports 1 study location spanning 1 distinct geographic area - top geographies include North Carolina.

Frequently Asked Questions

What is clinical trial NCT00137176 about?

NCT00137176 is a clinical study titled "EARLY IFNb-1a and Atorvastatin Combination Therapy of Isolated Clinical Syndrome Suggestive of Multiple Sclerosis". The primary purpose is to determine the changes in gene expression induced by IFNb-1a (Rebif) and atorvastatin (Lipitor) combination therapy in patients with an isolated clinical syndrome suggestive of multiple sclerosis (MS), to identify markers of therapeutic response, and to predict patients' cli...

What is the current status of trial NCT00137176?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2004-10. Estimated completion is 2008-10.

What conditions does trial NCT00137176 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT00137176?

The interventions under investigation include: Rebif (DRUG).

Who is sponsoring clinical trial NCT00137176?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00137176 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Multiple Sclerosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.