Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06136286 · ClinicalTrials.gov registry record · NA
ORIF Distal Radius Blood Flow Restriction Therapy
A NA study of Distal Radius Fractures, sponsored by The Methodist Hospital Research Institute.
- Active
- Registry status
- NA
- Development phase
- 70
- Enrollment target
- 1
- Study location
NCT06136286: Active NA study of Distal Radius Fractures, sponsored by The Methodist Hospital Research Institute.
NCT06136286 is a NA study of Distal Radius Fractures that is active but no longer recruiting, run by The Methodist Hospital Research Institute. The registered enrollment target is 70 participants, below the 179-participant average among 4 other Distal Radius Fractures trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06136286, a NA study of Distal Radius Fractures, is active but no longer recruiting, sponsored by The Methodist Hospital Research Institute.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 70 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients commonly experience a significant amount of muscular atrophy following open reduction internal fixation (ORIF) surgery of distal radius fractures, associated with an increased risk of re-injury, and an increase in time of recovery. A combination of low intensity resistance exercise and blood flow restriction (BFR) therapy has been shown to elicit responses similar to high intensity resistance exercise with reduced risk. We hypothesize that chronic low intensity resistance exercise combined with BFR will improve muscular strength, reduce skeletal muscle atrophy, and will enhance recovery. Therefore, the specific aims of this study are as follows: 1. Determine if BFR added to standard post-operative rehab will prevent skeletal muscle atrophy and promote skeletal muscle growth during 12-weeks of rehab training compared to traditional rehab alone. The working hypothesis, founded on previous literature, is that combined rehab and BFR will enhance skeletal muscle growth and prevent atrophy to a greater extent than rehab alone. 2. Determine if BFR added to standard post-operative rehab will improve muscular strength following surgery compared to traditional rehab alone. Because strength can be attributed to skeletal muscle mass, the working hypothesis, founded on previous literature, is that combined rehab and BFR will enhance skeletal muscle strength and fatigue resistance to a greater extent than rehab alone. 3. Determine if BFR added to standard post-operative rehab will improve functional outcomes following surgery compared to traditional rehab alone. The working hypothesis, founded on previous literature is that BFR will improve functional outcomes over rehab alone.
Primary Outcome
Soft tissue analysis of forearm and total body via DEXA scan.
Conditions Studied
Interventions
- DEVICE Blood Flow Restriction (BFR) Cuff
Study Locations (1)
Texas
- Houston Methodist Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 70 participants |
| Start Date | 2019-10-22 |
| Est. Completion | 2027-01-01 |
| Phase | NA |
What the registry record for NCT06136286 still lists
NCT06136286 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 70 participants, a relatively small participant target, below the 179-participant average among 4 other Distal Radius Fractures trials with a reported enrollment target (61% lower).
The record links to 1 condition, with Distal Radius Fractures appearing as the primary indexed condition, and to 1 intervention - of which Blood Flow Restriction (BFR) Cuff is the first listed.
NCT06136286 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06136286 about?
NCT06136286 is a clinical study titled "ORIF Distal Radius Blood Flow Restriction Therapy". Patients commonly experience a significant amount of muscular atrophy following open reduction internal fixation (ORIF) surgery of distal radius fractures, associated with an increased risk of re-injury, and an increase in time of recovery. A combination of low intensity resistance exercise and bloo...
What is the current status of trial NCT06136286?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 70 participants. The study started on 2019-10-22. Estimated completion is 2027-01-01.
What conditions does trial NCT06136286 study?
This clinical trial studies the following conditions: Distal Radius Fractures.
What interventions are being tested in trial NCT06136286?
The interventions under investigation include: Blood Flow Restriction (BFR) Cuff (DEVICE).
Who is sponsoring clinical trial NCT06136286?
This trial is sponsored by The Methodist Hospital Research Institute, which has 126 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06136286 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Distal Radius Fractures
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Is Sensorimotor Training Effective Following a Distal Radius Fracture?
RECRUITING · NA
-
Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Orthopedic Wrist Surgery
RECRUITING · Phase 3
-
Impact of Early ADL Education on Outcomes Post DRF ORIF
RECRUITING · Phase 1
-
Hematoma Block Versus Bier Block for Closed Fracture Reduction
ACTIVE NOT RECRUITING · Early Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00969111 · 70 participants · NA
Postoperative or Salvage Radiotherapy (RT) for Node Negative Prostate Cancer Following Radical Prostatectomy
- NCT01712620 · 70 participants · Phase 2
Spironolactone for Pulmonary Arterial Hypertension
- NCT02143830 · 70 participants · Phase 2
HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy
- NCT02601339 · 70 participants
NIRS Monitoring in Premature Infants
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI