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NCT03742245 · ClinicalTrials.gov registry record · Phase 1

Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer

A Phase 1 study of Breast Cancer and Breast Cancer Metastatic, sponsored by The Methodist Hospital Research Institute.

Active
Registry status
Phase 1
Development phase
28
Enrollment target
1
Study location

NCT03742245: Active Phase 1 study of Breast Cancer and Breast Cancer Metastatic, sponsored by The Methodist Hospital Research Institute.

NCT03742245 is a Phase 1 study of Breast Cancer and Breast Cancer Metastatic that is active but no longer recruiting, run by The Methodist Hospital Research Institute. The registered enrollment target is 28 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03742245, a Phase 1 study of Breast Cancer and Breast Cancer Metastatic, is active but no longer recruiting, sponsored by The Methodist Hospital Research Institute.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to test the safety and preliminary efficacy of olaparib and vorinostat when used together in participants with relapsed/refractory and or metastatic breast cancer.

Conditions Studied

Breast Cancer Breast Cancer Metastatic

Interventions

  • DRUG Olaparib
  • DRUG Vorinostat

Study Locations (1)

Texas

  • Houston Methodist Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2019-06-11
Est. Completion 2026-12-01
Phase Phase 1

Sponsor

The Methodist Hospital Research Institute

126 total trials

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What the Registry Record Tells You About NCT03742245

The ClinicalTrials.gov registry entry for NCT03742245 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The listed sponsor is The Methodist Hospital Research Institute, which has 126 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Olaparib is the first listed.

NCT03742245 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT03742245 about?

NCT03742245 is a clinical study titled "Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer". The purpose of this study is to test the safety and preliminary efficacy of olaparib and vorinostat when used together in participants with relapsed/refractory and or metastatic breast cancer.

What is the current status of trial NCT03742245?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 28 participants. The study started on 2019-06-11. Estimated completion is 2026-12-01.

What conditions does trial NCT03742245 study?

This clinical trial studies the following conditions: Breast Cancer, Breast Cancer Metastatic.

What interventions are being tested in trial NCT03742245?

The interventions under investigation include: Olaparib (DRUG), Vorinostat (DRUG).

Who is sponsoring clinical trial NCT03742245?

This trial is sponsored by The Methodist Hospital Research Institute, which has 126 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03742245 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.