The Medicines Company
The Medicines Company sponsors 35 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 32 completed. 24 of these trials are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Thrombosis, with 2 trials.
Trial Pipeline
35 total, page 1 of 1
Inclisiran for Participants With Atherosclerotic Cardiovascular Disease and Elevated Low-density Lipoprotein Cholesterol
NCT03399370
Trial to Evaluate the Effect of Inclisiran Treatment on Low Density Lipoprotein Cholesterol (LDL-C) in Subjects With Heterozygous Familial Hypercholesterolemia (HeFH)
NCT03397121
Safety of Either a Single or Two Intravenous Doses of Orbactiv in Participants With Acute Bacterial Skin and Skin Structure Infection
NCT02925416
A Study of ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH)
NCT02963311
Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C)
NCT02597127
A Study to Evaluate the Safety of a Single Intravenous (IV) Dose of Orbactiv (Oritavancin) in Participants on Chronic Warfarin Therapy Being Treated For Acute Bacterial Skin and Skin Structure Infection (ABSSSI)
NCT02452918
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of a New Formulation of Oritavancin in Healthy Volunteers
NCT02471690
Safety and Clinical Utility Study of SSEC Fentanyl 40 mcg for Acute Post-op Pain Management in Pediatric Participants
NCT02395653
Cangrelor to Clopidogrel or Prasugrel Transition Study
NCT01979445
ENDOvascular Interventions With AngioMAX: The ENDOMAX Trial
NCT01913483
Cangrelor Prasugrel Transition Study
NCT01852019
Cangrelor Ticagrelor Transition Study
NCT01766466
A Clinical Trial Comparing Cangrelor to Clopidogrel Standard Therapy in Subjects Who Require Percutaneous Coronary Intervention (PCI) (CHAMPION PHOENIX)
NCT01156571
Clevidipine in the Treatment of Blood Pressure in Patients With Acute Heart Failure (PRONTO)
NCT00803634
Clevidipine Bolus Administration in the Treatment of Hypertensive Patients Undergoing Cardiac Surgery (SPRINT)
NCT00799604
Maintenance of Platelet Inhibition With Cangrelor
NCT00767507
Clevidipine in the Treatment of Patients With Acute Hypertension and Intracerebral Hemorrhage (ACCELERATE)
NCT00666328
Assess the Effect of Cangrelor at the Therapeutic Dose and a Supratherapeutic Dose Level on the QT/QTc Interval in Healthy Volunteers
NCT00699504
Clevidipine in the Treatment of Patients With Severe Hypertension (VELOCITY)
NCT00369837
Cangrelor Versus Standard Therapy to Achieve Optimal Management of Platelet Inhibition.
NCT00385138
A Clinical Trial to Demonstrate the Efficacy of Cangrelor
NCT00305162
Pharmacokinetics/Pharmacodynamics (PK/PD) of Cangrelor
NCT00102674
Clevidipine in the Perioperative Treatment of Hypertension (ECLISPE-SNP)
NCT00093912
Clevidipine in the Postoperative Treatment of Hypertension (ECLIPSE-NIC)
NCT00093925
Angiomax in Patients With HIT/HITTS Type II Undergoing CPB
NCT00079508
Bivalirudin in Patients With Acute Myocardial Infarction (AMI) Undergoing Primary PCI
NCT00093184
Comparing Angiomax to Heparin With Protamine in Patients Undergoing Cardiopulmonary Bypass (CPB)
NCT00079586
Clevidipine in the Perioperative Treatment of Hypertension (ECLIPSE-NTG)
NCT00093886
Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1)
NCT00093249
Study of Clevidipine Assessing Its Postoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-2)
NCT00093262
Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE)
NCT00073580
Comparing Angiomax to Heparin With Protamine Reversal in Patients OPCAB
NCT00073593
Comparison of Angiomax Versus Heparin in Acute Coronary Syndromes (ACS)
NCT00093158
Study Of Angiomax In Infants Under Six Months With Thrombosis
NCT00043277
Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning)
NCT00043940
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 8 |
| Phase 3 | 22 |
| Phase 4 | 2 |
Therapeutic Areas
What the Pipeline for The Medicines Company Shows
According to the ClinicalTrials.gov registry, The Medicines Company is linked to 35 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 32 are already marked complete, representing roughly 91% of the total.
The phase mix for The Medicines Company reports 24 late-stage studies (Phase 3 and Phase 4 combined) and 11 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for The Medicines Company is Thrombosis with 2 linked trials, and 5 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.