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NCT00767507 · ClinicalTrials.gov registry record · Phase 2

Maintenance of Platelet Inhibition With Cangrelor

A Phase 2 study of Acute Coronary Syndrome (ACS), sponsored by The Medicines Company.

Completed
Registry status
Phase 2
Development phase
221
Enrollment target
1
Study location

NCT00767507: Completed Phase 2 study of Acute Coronary Syndrome (ACS), sponsored by The Medicines Company.

NCT00767507 is a Phase 2 study of Acute Coronary Syndrome (ACS) that has completed, run by The Medicines Company. The registered enrollment target is 221 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (66% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00767507, a Phase 2 study of Acute Coronary Syndrome (ACS), has completed, sponsored by The Medicines Company.

COMPLETED
Registry status
Phase 2
Development phase
221 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to demonstrate that patients receiving cangrelor infusion before coronary artery bypass grafting have an acceptable safety profile and can undergo surgery without excessive bleeding peri-operatively.

Primary Outcome

Endpoint was selected as an approximation of the antiplatelet effect expected to be maintained if oral P2Y12 inhibitors had not been discontinued (60% inhibition of platelets).

Interventions

  • OTHER Placebo
  • DRUG cangrelor

Study Locations (1)

California

  • Scripps Clinic / Scripps Green Hospital - La Jolla

Trial Details

FieldValue
Enrollment Target 221 participants
Start Date 2008-10
Est. Completion 2011-07
Phase Phase 2
The Medicines Company

35 total trials

What the finished NCT00767507 record still lists

NCT00767507 is an interventional study that assigns participants to a tested intervention. The registered 221 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (66% higher).

The record links to 1 condition, with Acute Coronary Syndrome (ACS) appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT00767507 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT00767507 about?

NCT00767507 is a clinical study titled "Maintenance of Platelet Inhibition With Cangrelor". The purpose of this study is to demonstrate that patients receiving cangrelor infusion before coronary artery bypass grafting have an acceptable safety profile and can undergo surgery without excessive bleeding peri-operatively.

What is the current status of trial NCT00767507?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 221 participants. The study started on 2008-10. Estimated completion is 2011-07.

What conditions does trial NCT00767507 study?

This clinical trial studies the following conditions: Acute Coronary Syndrome (ACS).

What interventions are being tested in trial NCT00767507?

The interventions under investigation include: Placebo (OTHER), cangrelor (DRUG).

Who is sponsoring clinical trial NCT00767507?

This trial is sponsored by The Medicines Company, which has 35 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00767507 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Acute Coronary Syndrome (ACS)

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00767507's enrollment target sits among peer trials

221 275th of 2000 higher than 1,726 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00767507, the US trial registry maintained by the National Library of Medicine. NCT00767507 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.