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NCT00093249 · ClinicalTrials.gov registry record · Phase 3

Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1)

A Phase 3 study, sponsored by The Medicines Company.

Completed
Registry status
Phase 3
Development phase
105
Enrollment target

NCT00093249: Completed Phase 3 study, sponsored by The Medicines Company.

NCT00093249 is a Phase 3 study that has completed, run by The Medicines Company. The registered enrollment target is 105 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (86% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00093249, a Phase 3 study, has completed, sponsored by The Medicines Company.

COMPLETED
Registry status
Phase 3
Development phase
105 participants
Enrollment target

Study Summary

The purpose of this study is to determine the efficacy of clevidipine injection versus placebo in treating preoperative hypertension.

Primary Outcome

discontinuation of study drug categorized according to the following reasons: * Bailout for lack of efficacy * Bailout for safety reason(s) * Bailout due to treatment failure

Interventions

  • DRUG placebo
  • DRUG clevidipine

Trial Details

FieldValue
Enrollment Target 105 participants
Start Date 2004-01
Est. Completion 2004-11
Phase Phase 3
The Medicines Company

35 total trials

What the finished NCT00093249 record still lists

NCT00093249 is an interventional study that assigns participants to a tested intervention. The registered 105 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (86% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT00093249 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00093249 about?

NCT00093249 is a clinical study titled "Study of Clevidipine Assessing Its Preoperative Antihypertensive Effect in Cardiac Surgery (ESCAPE-1)". The purpose of this study is to determine the efficacy of clevidipine injection versus placebo in treating preoperative hypertension.

What is the current status of trial NCT00093249?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 105 participants. The study started on 2004-01. Estimated completion is 2004-11.

What interventions are being tested in trial NCT00093249?

The interventions under investigation include: placebo (DRUG), clevidipine (DRUG).

Who is sponsoring clinical trial NCT00093249?

This trial is sponsored by The Medicines Company, which has 35 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00093249's enrollment target sits among peer trials

105 1670th of 2000 higher than 330 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00093249, the US trial registry maintained by the National Library of Medicine. NCT00093249 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.