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NCT00305162 · ClinicalTrials.gov registry record · Phase 3

A Clinical Trial to Demonstrate the Efficacy of Cangrelor

A Phase 3 study, sponsored by The Medicines Company.

Terminated
Registry status
Phase 3
Development phase
8,882
Enrollment target

NCT00305162: Clinical Trial Phase 3 study, sponsored by The Medicines Company.

NCT00305162 is a Phase 3 study that was terminated before completion, run by The Medicines Company. The registered enrollment target is 8,882 participants, above the 771-participant average among 15,282 other Phase 3 trials with a reported enrollment target (1052% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00305162, a Phase 3 study, was terminated before completion, sponsored by The Medicines Company.

TERMINATED
Registry status
Phase 3
Development phase
8,882 participants
Enrollment target

Study Summary

The primary objective of this study is to demonstrate that the efficacy of cangrelor is superior, or at least non-inferior, to that of clopidogrel in subjects requiring PCI.

Primary Outcome

(composite incidence)

Interventions

  • DRUG Placebo bolus & placebo infusion
  • DRUG Placebo capsules - end of infusion
  • DRUG Cangrelor (P2Y12 inhibitor)
  • DRUG clopidogrel (oral P2Y12 inhibitor)
  • DRUG Placebo capsules - as soon as possible after randomization

Trial Details

FieldValue
Enrollment Target 8,882 participants
Start Date 2006-04
Est. Completion 2010-06
Phase Phase 3
The Medicines Company

35 total trials

Why NCT00305162 stopped before completion

NCT00305162 is an interventional study that assigns participants to a tested intervention. Its 8,882 participants enrollment target places it among the larger protocols in the corpus, above the 771-participant average among 15,282 other Phase 3 trials with a reported enrollment target (1052% higher).

The record links to 0 conditions, and to 5 interventions - of which Placebo bolus & placebo infusion is the first listed.

NCT00305162 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00305162 about?

NCT00305162 is a clinical study titled "A Clinical Trial to Demonstrate the Efficacy of Cangrelor". The primary objective of this study is to demonstrate that the efficacy of cangrelor is superior, or at least non-inferior, to that of clopidogrel in subjects requiring PCI.

What is the current status of trial NCT00305162?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 8,882 participants. The study started on 2006-04. Estimated completion is 2010-06.

What interventions are being tested in trial NCT00305162?

The interventions under investigation include: Placebo bolus & placebo infusion (DRUG), Placebo capsules - end of infusion (DRUG), Cangrelor (P2Y12 inhibitor) (DRUG), clopidogrel (oral P2Y12 inhibitor) (DRUG), Placebo capsules - as soon as possible after randomization (DRUG).

Who is sponsoring clinical trial NCT00305162?

This trial is sponsored by The Medicines Company, which has 35 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00305162's enrollment target sits among peer trials

8,882 32nd of 2000 higher than 1,969 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00305162, the US trial registry maintained by the National Library of Medicine. NCT00305162 (large enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.