Smith & Nephew
Smith & Nephew sponsors 72 registered US clinical trials on ClinicalTrials.gov, 3 of them currently recruiting, and 39 completed. 4 of these trials are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Total Knee Arthroplasty, with 3 trials.
Trial Pipeline
72 total, page 2 of 2
TITAN™ Reverse Shoulder System
NCT02204228
Post-Market Evaluation of the Rotation Medical Rotator Cuff System
NCT02200939
A RCT to Compare the Effects of Two Wound Products on Biofilm Disruption in DFUs
NCT02181621
Mechanical vs. Radiofrequency-Based Debridement in the Treatment of Articular Cartilage Lesions
NCT01803880
Visionaire™ Versus Standard Instrumentation Safety and Efficacy in Total Knee Arthroplasty (TKA)
NCT01084772
PICO Breast Reduction Clinical Study Looking at Incision Healing Complications
NCT01640366
Safety and Efficacy of the Journey II BCS Total Knee System
NCT01705067
TRIGEN SURESHOT™ Distal Targeting System Study
NCT01327508
VISIONAIRE™ Value Study
NCT01107769
R3® Acetabular System in Patients With Degenerative Hip Disease
NCT01407029
LEGION™ Primary Safety and Efficacy
NCT04040985
Ascension PyroCarbon Radial Head Study
NCT02405234
Evaluation of the Use of EZCare/V1STA in the Management of Acute and Chronic Wounds
NCT00994162
Knee Articular Cartilage Debridement in Conjunction With Partial Meniscectomy
NCT00613535
INTUIT Hip Fracture Outcome Study
NCT00595634
Trial of Versajet Compared With Conventional Treatment in Acute and Chronic Wounds
NCT01050673
Ankle Joint Replacement Outcomes Study
NCT00503438
A Safety and Efficacy Study of the Birmingham Hip Resurfacing System
NCT00611585
A Study of Patients Treated With the Journey Deuce Bicompartmental Knee System
NCT01704326
Study Comparing VERSAJET With Conventional Surgical Procedures in the Removal of Unhealthy Tissue From Lower Limb Ulcers
NCT00521027
Safety and Effectiveness Study of the Reflection Ceramic Acetabular System
NCT00663351
Ascension® Post- Approval Study; PyroCarbon Metacarpophalangeal Total Joint Prosthesis
NCT02408471
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 4 |
What the Pipeline for Smith & Nephew Shows
According to the ClinicalTrials.gov registry, Smith & Nephew is linked to 72 US clinical trials across every stage of research activity. Of those, 3 studies are currently recruiting, about 4% of the sponsor's indexed portfolio, and 39 are already marked complete, representing roughly 54% of the total.
The phase mix for Smith & Nephew reports 4 late-stage studies (Phase 3 and Phase 4 combined) and 0 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Smith & Nephew is Total Knee Arthroplasty with 3 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.