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NCT03299959 · ClinicalTrials.gov registry record · NA
Agili-C™ Implant Performance Evaluation
A NA study, sponsored by Smith & Nephew.
- Completed
- Registry status
- NA
- Development phase
- 251
- Enrollment target
NCT03299959: Completed NA study, sponsored by Smith & Nephew.
NCT03299959 is a NA study that has completed, run by Smith & Nephew. The registered enrollment target is 251 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03299959, a NA study, has completed, sponsored by Smith & Nephew.
- COMPLETED
- Registry status
- NA
- Development phase
- 251 participants
- Enrollment target
Study Summary
The current study compares the efficacy and safety of the Agili-C implant to Surgical Standard of Care treatment in patients suffering from joint surface lesions of the knee. The patient population is heterogeneous, involving different kinds of joint surface lesions: focal cartilage lesions, osteochondral defects and mild to moderate osteoarthritis, including multiple defects.
Primary Outcome
Change from Baseline to 60 Months in Knee Injury and Osteoarthritis Outcome Score (KOOS) Overall Score measured by the five subscales of Pain (9 items), ADL function (17 items), Sport and Recreation Function (5 items), Symptoms (7 items), and Quality of Life (4 items). A Likert scale is used for all items with five possible answer options scored from 0 (no problems) to 4 (extreme problems). Each of the subscale scores are combined to calculate the KOOS Overall Score. The Overall Score is transfo
Interventions
- DEVICE Agili-C implant
- PROCEDURE SSOC
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 251 participants |
| Start Date | 2017-09-25 |
| Est. Completion | 2024-11-14 |
| Phase | NA |
What the finished NCT03299959 record still lists
NCT03299959 is an interventional study that assigns participants to a tested intervention. The registered 251 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (82% lower).
The record links to 0 conditions, and to 2 interventions - of which Agili-C implant is the first listed.
NCT03299959 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03299959 about?
NCT03299959 is a clinical study titled "Agili-C™ Implant Performance Evaluation". The current study compares the efficacy and safety of the Agili-C implant to Surgical Standard of Care treatment in patients suffering from joint surface lesions of the knee. The patient population is heterogeneous, involving different kinds of joint surface lesions: focal cartilage lesions, osteoch...
What is the current status of trial NCT03299959?
This trial is currently completed. It is a NA study. The enrollment target is 251 participants. The study started on 2017-09-25. Estimated completion is 2024-11-14.
What interventions are being tested in trial NCT03299959?
The interventions under investigation include: Agili-C implant (DEVICE), SSOC (PROCEDURE).
Who is sponsoring clinical trial NCT03299959?
This trial is sponsored by Smith & Nephew, which has 72 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03299959's enrollment target sits among peer trials
251 410th of 2000 higher than 1,591 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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