Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07199738 · ClinicalTrials.gov registry record
A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)
A clinical trial, sponsored by Smith & Nephew.
- Not yet
- Registry status
- 144
- Enrollment target
NCT07199738: Clinical Trial study, sponsored by Smith & Nephew.
NCT07199738 is a clinical trial that has not yet begun recruiting, run by Smith & Nephew. The registered enrollment target is 144 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07199738 has not yet begun recruiting, sponsored by Smith & Nephew.
- NOT YET RECRUITING
- Registry status
- 144 participants
- Enrollment target
Study Summary
The purpose of this study is to assess the long-term safety and performance of the LEGION Medial Stabilized insert and to generate clinical evidence to support and maintain product registration in global markets.
Primary Outcome
Implant survivorship at 10 years post-surgery. Implant survivorship is defined as the cumulative proportion of knee-implanted components without a revision. Survivorship is defined as absence of revision of any, or all, of the tibial / femoral / insert components that were implanted during the primary TKA - not including the patella. (Revision is the removal of some, or all, of the above specified implant components, and replacement with new ones for any reason).
Interventions
- DEVICE Cemented CoCr
- DEVICE Cemented Oxinium
- DEVICE Cementless
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 144 participants |
| Start Date | 2025-11 |
| Est. Completion | 2036-12 |
What is known before NCT07199738 opens enrollment
NCT07199738 is an observational study that tracks outcomes without assigning an intervention. The registered 144 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 3 interventions - of which Cemented CoCr is the first listed.
NCT07199738 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07199738 about?
NCT07199738 is a clinical study titled "A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)". The purpose of this study is to assess the long-term safety and performance of the LEGION Medial Stabilized insert and to generate clinical evidence to support and maintain product registration in global markets.
What is the current status of trial NCT07199738?
This trial is currently not yet recruiting. The enrollment target is 144 participants. The study started on 2025-11. Estimated completion is 2036-12.
What interventions are being tested in trial NCT07199738?
The interventions under investigation include: Cemented CoCr (DEVICE), Cemented Oxinium (DEVICE), Cementless (DEVICE).
Who is sponsoring clinical trial NCT07199738?
This trial is sponsored by Smith & Nephew, which has 72 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01861106 · 144 participants · Phase 2
Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations
- NCT03482245 · 144 participants · NA
The Role of Circadian Clock Proteins in Innate and Adaptive Immunity
- NCT03504683 · 144 participants · NA
MEAL TIMING Study: Effect of Time-Restricted Feeding on 24-hour Glycemic Control, Blood Pressure, and Cardiovascular Disease Risk Factors in Adults With Prediabetes
- NCT03905603 · 144 participants · Early Phase 1
Relative Contributions of Predictors of Hyperandrogenism in Older vs. Young Women With PCOS
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia