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NCT04585945 · ClinicalTrials.gov registry record

COVID-19 on Placental Gene Expression and Pathology

A clinical trial, sponsored by Prisma Health-Upstate.

Completed
Registry status
68
Enrollment target

NCT04585945 is a clinical trial that has completed, run by Prisma Health-Upstate. The registered enrollment target is 68 participants.

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The verdict

NCT04585945 has completed, sponsored by Prisma Health-Upstate.

COMPLETED
Registry status
68 participants
Enrollment target

Study Summary

Little is known regarding the effect of antenatal COVID-19 on pregnancy outcomes. The purpose of this study is to determine of COVID-19 alters histopathology and gene expression of the placenta, as evidenced by analysis at time of delivery. The analysis will aim to identify whether resulting abnormal placental pathology or altered metabolism is associated with severity of symptoms (specifically pneumonia, or need for admission), gestational age at onset, and/or placenta efficiency. Histological and gene expression analysis of the placental post-delivery will determine if COVID-19 alters overall placental structure, vascularization, and/or the transcriptome.

Interventions

  • DIAGNOSTIC_TEST Positive for SARS-CoV-2 infection

Trial Details

FieldValue
Enrollment Target 68 participants
Start Date 2020-08-04
Est. Completion 2022-02-28

Sponsor

Prisma Health-Upstate

67 total trials

What the Registry Record Tells You About NCT04585945

The ClinicalTrials.gov registry entry for NCT04585945 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 68 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Prisma Health-Upstate, which has 67 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Positive for SARS-CoV-2 infection is the first listed.

NCT04585945 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT04585945 about?

NCT04585945 is a clinical study titled "COVID-19 on Placental Gene Expression and Pathology". Little is known regarding the effect of antenatal COVID-19 on pregnancy outcomes. The purpose of this study is to determine of COVID-19 alters histopathology and gene expression of the placenta, as evidenced by analysis at time of delivery. The analysis will aim to identify whether resulting abnorma...

What is the current status of trial NCT04585945?

This trial is currently completed. The enrollment target is 68 participants. The study started on 2020-08-04. Estimated completion is 2022-02-28.

What interventions are being tested in trial NCT04585945?

The interventions under investigation include: Positive for SARS-CoV-2 infection (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT04585945?

This trial is sponsored by Prisma Health-Upstate, which has 67 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.