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NCT04790279 · ClinicalTrials.gov registry record · Phase 4
Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension
A Phase 4 study, sponsored by Prisma Health-Upstate.
- Completed
- Registry status
- Phase 4
- Development phase
- 175
- Enrollment target
NCT04790279: Completed Phase 4 study, sponsored by Prisma Health-Upstate.
NCT04790279 is a Phase 4 study that has completed, run by Prisma Health-Upstate. The registered enrollment target is 175 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (66% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04790279, a Phase 4 study, has completed, sponsored by Prisma Health-Upstate.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 175 participants
- Enrollment target
Study Summary
A significant number of pregnancies are complicated by hypertensive disorders. Hypertension often worsens in the postpartum period and many women need started on medications. Currently, recommended medications for blood pressure management in pregnant and postpartum women are limited, with labetalol and nifedipine ER being the most commonly used medications. While these medications are both effective, they are not without limitations. Amlodipine is a medication in the same class as nifedipine ER. It is a first-line antihypertensive in the general population. It tends to have less side effects than nifedipine ER. It has not been studied specifically in postpartum women. The purpose of this study is to determine if amlodipine is noninferior to nifedipine ER in managing hypertension in the postpartum period.
Primary Outcome
length of stay from delivery until discharge
Interventions
- DRUG Amlodipine
- DRUG NIFEdipine ER
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 175 participants |
| Start Date | 2021-04-09 |
| Est. Completion | 2023-01-25 |
| Phase | Phase 4 |
What the finished NCT04790279 record still lists
NCT04790279 is an interventional study that assigns participants to a tested intervention. The registered 175 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (66% lower).
The record links to 0 conditions, and to 2 interventions - of which Amlodipine is the first listed.
NCT04790279 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04790279 about?
NCT04790279 is a clinical study titled "Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension". A significant number of pregnancies are complicated by hypertensive disorders. Hypertension often worsens in the postpartum period and many women need started on medications. Currently, recommended medications for blood pressure management in pregnant and postpartum women are limited, with labetalol...
What is the current status of trial NCT04790279?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 175 participants. The study started on 2021-04-09. Estimated completion is 2023-01-25.
What interventions are being tested in trial NCT04790279?
The interventions under investigation include: Amlodipine (DRUG), NIFEdipine ER (DRUG).
Who is sponsoring clinical trial NCT04790279?
This trial is sponsored by Prisma Health-Upstate, which has 67 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04790279's enrollment target sits among peer trials
175 478th of 2000 higher than 1,521 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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