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NCT04014777 · ClinicalTrials.gov registry record · Phase 1
Study of NGM621 in Participants With Geographic Atrophy
A Phase 1 study, sponsored by NGM Biopharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
NCT04014777: Completed Phase 1 study, sponsored by NGM Biopharmaceuticals.
NCT04014777 is a Phase 1 study that has completed, run by NGM Biopharmaceuticals. The registered enrollment target is 15 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04014777, a Phase 1 study, has completed, sponsored by NGM Biopharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
Study Summary
This is a multi-center evaluation of NGM621 in an open-label, single-dose and multiple-dose escalation study in participants with Geographic Atrophy secondary to Age-related Macular Degeneration.
Primary Outcome
The number and percent of patients reporting treatment emergent adverse events (TEAEs) by cohort.
Interventions
- BIOLOGICAL NGM621
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2019-07-26 |
| Est. Completion | 2020-05-27 |
| Phase | Phase 1 |
What the finished NCT04014777 record still lists
NCT04014777 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (75% lower).
The record links to 0 conditions, and to 1 intervention - of which NGM621 is the first listed.
NCT04014777 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT04014777 about?
NCT04014777 is a clinical study titled "Study of NGM621 in Participants With Geographic Atrophy". This is a multi-center evaluation of NGM621 in an open-label, single-dose and multiple-dose escalation study in participants with Geographic Atrophy secondary to Age-related Macular Degeneration.
What is the current status of trial NCT04014777?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2019-07-26. Estimated completion is 2020-05-27.
What interventions are being tested in trial NCT04014777?
The interventions under investigation include: NGM621 (BIOLOGICAL).
Who is sponsoring clinical trial NCT04014777?
This trial is sponsored by NGM Biopharmaceuticals, which has 18 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT04014777's enrollment target sits among peer trials
15 1798th of 2000 higher than 157 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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