CytoDyn

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, CytoDyn sits in the top decile of US sponsors by registered trial count (#801 of 15,742 sponsors by registered trial count).

18 total trials 1 currently recruiting 13 completed early-phase tilt top decile by trial count

CytoDyn: 18 sponsored US clinical trials, 1 recruiting.

CytoDyn sponsors 18 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 13 completed. 0 of these trials are in Phase 3-4 (later-stage) and 17 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Coronavirus Disease 2019, with 2 trials.

Top-decile sponsor footprint

CytoDyn ranks in the top decile of sponsors by registered trial count (#801 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 30/100

13 of 17 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (76.5%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

18 total, page 1 of 1

RECRUITING Phase 2

A Phase 2 Study of Leronlimab in Combination With TAS-102 + Bevacizumab in Previously Treated Participants With mCRC

NCT06699836

COMPLETED Phase 2

Double Blind, Placebo Controlled Study of Safety and Efficacy of Leronlimab in Patients With "Long" COVID-19

NCT04678830

COMPLETED Phase 2

Leronlimab (PRO 140) in Patients With Nonalcoholic Steatohepatitis

NCT04521114

COMPLETED Phase 2

Basket Study of Leronlimab (PRO 140) in Patients With CCR5+ Locally Advanced or Metastatic Solid Tumors

NCT04504942

COMPLETED Phase 2

Evaluate the Efficacy & Safety of Leronlimab in Patients With Severe or Critical COVID-19

NCT04347239

COMPLETED Phase 2

Study to Evaluate the Efficacy and Safety of Leronlimab for Mild to Moderate COVID-19

NCT04343651

TERMINATED Phase 1

Leronlimab (PRO 140) Combined With Carboplatin in Patients With Cytokine Chemokine Receptor 5 Positive (CCR5+) mTNBC

NCT03838367

COMPLETED Phase 2

PRO 140 in Treatment-Experienced HIV-1 Subjects

NCT03902522

TERMINATED Phase 2

An Extension Protocol for Virologically Suppressed Subjects Who Successfully Completed PRO140_CD03 Study

NCT05271370

TERMINATED Phase 2

A Study of Acute Graft-Versus-Host Disease (GVHD) in Patients Undergoing Allogeneic Stem-Cell Transplantation

NCT02737306

COMPLETED Phase 2

Study of PRO 140 SC as Single Agent Maintenance Therapy in Virally Suppressed Subjects With CCR5-tropic HIV-1 Infection

NCT02859961

COMPLETED Phase 2

Randomized, Double-Blind, Placebo-Controlled Trial, Followed by Single-Arm Treatment of PRO 140

NCT02483078

TERMINATED Phase 2

An Extension of Protocol PRO 140_CD01 Study

NCT02355184

COMPLETED Phase 2

Treatment Substitution With PRO 140 Monotherapy in Adult Subjects With HIV-1 Infection

NCT02175680

COMPLETED

Observational Study of Blood Treated With Cytolin

NCT01048372

COMPLETED Phase 2

Study of PRO 140 by Subcutaneous Administration in Adult Subjects With HIV -1 Infection

NCT00642707

COMPLETED Phase 2

PRO 140 by IV Administration in Adults With HIV-1 Infection

NCT00613379

COMPLETED Phase 1

Safety and Tolerability of PRO 140 in HIV Uninfected Male Volunteers

NCT00110591

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 15

What is open in the CytoDyn pipeline

1 recruiting of 18 indexed (6% open); 13 completed (72%).

Phase mix: 0 late (III/IV) vs 17 early (I/II) (early-phase heavy).

Top condition: Coronavirus Disease 2019 (2 trials), 1 other listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

CytoDyn: open-pipeline peers nationwide

Peers matched on 18 registered trials and 6% open enrollment, not the therapeutic-area sidebar.

CytoDyn sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 17.917.91818.1 0%10%20%30%40% Total trials Recruiting share CytoDynADC Therapeutics S.A.Akros PharmaAO Clinical Investigation and Publishing DocumentationAO Innovation Translation CenterBoston CollegeDendreonIntercept PharmaceuticalsNGM Biopharmaceuticals
CytoDyn sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

CytoDyn sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 18 trials (± recruiting share)

Sponsors near 6% open enrollment (± trial volume)

What to do with this CytoDyn page

18 registered trials is a research-attention snapshot, not an endorsement of CytoDyn or any single study.

  • 1 of CytoDyn's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Coronavirus Disease 2019 is the condition CytoDyn studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Coronavirus Disease 2019 trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

CytoDyn pipeline card: 18 registered trials from official public datasets.Report a data error.