National Institute of Allergy and Infectious Diseases (NIAID)

2,006 total trials 155 currently recruiting 1642 completed

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Trial Pipeline

2,006 total, page 39 of 41

COMPLETED Phase 1

Phase I Pharmacokinetic and Tolerance Study of Ribavirin in Human Immunodeficiency Virus (HIV) - Infected Patients

NCT00000733

COMPLETED Phase 2

Handheld Computers to Improve Adherence to Anti-HIV Drug Regimens

NCT00053443

COMPLETED Phase 2

A Phase II, Comparative Study of Seroconversion of Single-Dose and Two-Dose Measles Vaccination in HIV-Infected and HIV-Uninfected Children: A Multicenter Trial of the Pediatric AIDS Clinical Trials Group

NCT00000815

COMPLETED Phase 1

A Phase I Trial To Evaluate the Safety and Immunogenicity of the UBI HIV-1MN PND Peptide Immunogen, Given by IM Injection, in Combination With the UBI Microparticulate Monovalent HIV-1 MN Branched Peptide Given Orally, in HIV-1 Uninfected Volunteers.

NCT00000846

COMPLETED NA

A Study of Zidovudine in HIV-Infected Patients With Liver Disease

NCT00001001

COMPLETED Phase 1

A Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of 100 mcg of Env 2-3 in MF59

NCT00000632

COMPLETED Phase 1

A Study on the Effect of Chemotherapy Combined With Anti-HIV Drugs in HIV-Positive Patients

NCT00000899

COMPLETED Phase 2

A Study to Compare Two Anti-HIV Combination Therapies Each Containing Saquinavir in HIV-Positive Children

NCT00000913

COMPLETED Phase 3

A Study of Nevirapine to Prevent HIV Transmission From Mothers to Their Infants

NCT00001135

COMPLETED Phase 1

The Safety and Effectiveness of Injections of Human Recombinant Interferon-gamma in Patients With AIDS Who Have Taken Zidovudine

NCT00001112

COMPLETED Phase 2

A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive Children

NCT00000811

COMPLETED Phase 1

A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP

NCT00000998

COMPLETED Phase 1

A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Immuno-AG Recombinant HIV gp160 in Asymptomatic HIV Seropositive Individuals

NCT00000633

COMPLETED Phase 1

Effectiveness of Anti-HIV Therapy (HAART) in HIV-Infected Patients With Tuberculosis

NCT00004736

COMPLETED Phase 1

Interactions of HIV Protease Inhibitors and Methadone in HIV-Infected Patients

NCT00000906

COMPLETED NA

Pilot Study to Evaluate the Efficacy of Zidovudine in Preventing CD4+ Lymphocyte Decline in Patients With Primary HIV Infection. (One Treatment Arm Receives Placebo)

NCT00000765

COMPLETED Phase 3

The Safety and Effectiveness of Zidovudine in the Treatment of Patients With Early AIDS Related Complex

NCT00001011

COMPLETED Phase 3

Antibiotics to Reduce Chorioamnionitis-Related Perinatal HIV Transmission

NCT00021671

COMPLETED NA

A Study to Evaluate the Ability of TNFR:Fc to Decrease the Amount of IL-6 (Interleukin-6) and TNF-alpha (Tumor Necrosis Factor) in HIV-Infected Patients

NCT00001116

COMPLETED Phase 2

A Study on Amprenavir in Combination With Other Anti-HIV Drugs in HIV-Positive Patients

NCT00000912

COMPLETED Phase 2

(Ro 24-2027) A Randomized, Double-Blind, Comparative Study of Dideoxycytidine (ddC) Versus Zidovudine (AZT) in Patients With AIDS or Advanced ARC

NCT00000679

COMPLETED NA

A Study of Nevirapine Used Alone or in Combination With AZT in HIV-1-Infected Children

NCT00001111

COMPLETED

Use of a Test That Evaluates How the Body Handles Insulin and Glucose

NCT00027092

COMPLETED Phase 3

A Study of Pentamidine Plus Dapsone in the Prevention of Pneumocystis Carinii Pneumonia (PCP) in HIV-Infected Patients Who Cannot Take Trimethoprim or Sulfonamides

NCT00001028

COMPLETED Phase 1

Safety and Tolerability of the Vaginal Gel PRO 2000/5

NCT00006207

COMPLETED Phase 1

A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia-Derived HIV-1 Recombinant Envelope Glycoprotein (gp160)

NCT00000968

COMPLETED Phase 1

Evaluation of the Changes in HIV-1 Burden in Peripheral Blood and Lymphoid Tissue Following Zidovudine ( AZT ) Treatment in HIV-1-Infected Patients With CD4+ Cells Between 100 and 500 Cells/mm3.

NCT00000818

COMPLETED NA

Interleukin-2 (IL-2) Treatment for HIV Infected Patients Who Have Interrupted Their Anti-HIV Drug Therapy

NCT00038259

COMPLETED NA

Multi-center Comparison of Fluconazole (UK-49,858) and Amphotericin B as Treatment for Acute Cryptococcal Meningitis

NCT00000708

COMPLETED Phase 2

Thalidomide for Treatment of Oral and Esophageal Aphthous Ulcers and HIV Viremia in Patients With HIV Infection

NCT00000790

COMPLETED Phase 3

Addition of Efavirenz or Nelfinavir to a Lamivudine/Zidovudine/Indinavir HIV Treatment Regimen

NCT00000903

COMPLETED

The Effects of Anti-HIV Drugs on the HIV Virus in HIV-Infected Patients

NCT00006442

COMPLETED Phase 1

A Study of the Effects of Advantage 24 on the Rectum

NCT00000929

COMPLETED Phase 1

A Study of Foscarnet Plus Ganciclovir in the Treatment of Cytomegalovirus of the Eye in Patients With AIDS Who Have Already Been Treated With Ganciclovir

NCT00000970

COMPLETED Phase 2

A Phase II, Double-Blind Trial of Recombinant Human Nerve Growth Factor for Treatment of HIV-Associated Sensory Neuropathy

NCT00000842

COMPLETED Phase 3

Safety and Effectiveness of Fenofibrate and Pravastatin in HIV-Positive Patients With Abnormal Blood Lipids

NCT00006412

COMPLETED Phase 1

A Phase I Multicenter Clinical Trial to Evaluate the Safety and Immunogenicity of Vaccinia Derived HIV-1 Recombinant Envelope Glycoprotein (gp160) of Human Immunodeficiency Virus: Evaluation of a 200-mcg Dose

NCT00001056

COMPLETED Phase 1

Safety and Effectiveness of Azidothymidine (AZT) in HIV-Positive Patients With Hemophilia

NCT00000705

COMPLETED Phase 2

A Study of Azidothymidine in HIV-Infected Children

NCT00000982

COMPLETED Phase 1

Safety of and Immune Response to a Combination HIV Vaccine Regimen in HIV Uninfected Adults

NCT00073216

COMPLETED Phase 1

A Phase I Multicenter Study of the Safety and Immunogenicity of MN rgp120/HIV-1 Vaccine Given Either Alone or in Combination With IIIB rgp120/HIV-1 Vaccine in Healthy Adult Subjects (NOTE: Original Study Extended ONLY for Patients Previously Enrolled on VEU 009)

NCT00001021

COMPLETED Phase 1

The Effect of Stomach Acid on Foscarnet

NCT00000964

COMPLETED Phase 2

Safety and Acceptability of a Vaginal Microbicide

NCT00111943

COMPLETED Phase 2

A Multicenter Trial To Evaluate Oral Retrovir in the Treatment of Children With Symptomatic HIV Infection

NCT00000716

COMPLETED Phase 3

A Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial of the Safety and Efficacy of Ceftriaxone and Doxycycline in the Treatment of Patients With Seropositive Chronic Lyme Disease

NCT00001101

COMPLETED Phase 1

A Phase I Study of the Safety and Immunogenicity of rgp120/HIV-1IIIB Vaccine in Healthy Adult Subjects (NOTE: Study Extended ONLY for Subjects Who Have Previously Received rgp120/HIV-1IIIB or rgp120/HIV-1MN on VEU 006 or VEU 006 Rollover Study)

NCT00001020

COMPLETED

Observing Patients With Early HIV Infection

NCT00005020

COMPLETED Phase 3

A Multi-Center Clinical Trial To Evaluate Azidothymidine (AZT) in the Treatment of Human Immunodeficiency Virus (HIV) Infection in Patients With AIDS Post First Episode PCP

NCT00000700

COMPLETED NA

Vitamin B Therapy for Hyperlactatemia

NCT00031057

COMPLETED

Effects of Ribavirin on Zidovudine or Stavudine

NCT00021632

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What the Pipeline for National Institute of Allergy and Infectious Diseases (NIAID) Shows

According to the ClinicalTrials.gov registry, National Institute of Allergy and Infectious Diseases (NIAID) is linked to 2,006 US clinical trials across every stage of research activity. Of those, 155 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 1,642 are already marked complete, representing roughly 82% of the total.

The phase mix for National Institute of Allergy and Infectious Diseases (NIAID) reports 177 late-stage studies (Phase 3 and Phase 4 combined) and 1,291 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Allergy and Infectious Diseases (NIAID) is HIV Infections with 195 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.