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NCT00000998 · ClinicalTrials.gov registry record · Phase 1

A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP

A Phase 1 study, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
Phase 1
Development phase
50
Enrollment target

NCT00000998 is a Phase 1 study that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 50 participants.

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The verdict

NCT00000998, a Phase 1 study, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
Phase 1
Development phase
50 participants
Enrollment target

Study Summary

To evaluate the safety and effectiveness of trimetrexate (TMTX) given at increasing doses along with the leucovorin calcium (LCV) for treating Pneumocystis carinii pneumonia (PCP) in AIDS patients TMTX is an experimental new drug which is effective for treatment of PCP, but has been given to only a few patients. Therefore it is not certain if TMTX is better, the same as, or not as effective as conventional drugs against PCP.

Interventions

  • DRUG Leucovorin calcium
  • DRUG Trimetrexate glucuronate

Trial Details

FieldValue
Enrollment Target 50 participants
Est. Completion 1989-04
Phase Phase 1

What the Registry Record Tells You About NCT00000998

The ClinicalTrials.gov registry entry for NCT00000998 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Leucovorin calcium is the first listed.

NCT00000998 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00000998 about?

NCT00000998 is a clinical study titled "A Study of Trimetrexate in the Treatment of Pneumocystis Carinii Pneumonia (PCP) in Patients With AIDS Not Previously Treated for PCP". To evaluate the safety and effectiveness of trimetrexate (TMTX) given at increasing doses along with the leucovorin calcium (LCV) for treating Pneumocystis carinii pneumonia (PCP) in AIDS patients TMTX is an experimental new drug which is effective for treatment of PCP, but has been given to only a ...

What is the current status of trial NCT00000998?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 50 participants. Estimated completion is 1989-04.

What interventions are being tested in trial NCT00000998?

The interventions under investigation include: Leucovorin calcium (DRUG), Trimetrexate glucuronate (DRUG).

Who is sponsoring clinical trial NCT00000998?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.