National Institute of Allergy and Infectious Diseases (NIAID)

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, National Institute of Allergy and Infectious Diseases (NIAID) sits in the top decile of US sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count).

2,006 total trials 155 currently recruiting 1642 completed early-phase tilt top decile by trial count

National Institute of Allergy and Infectious Diseases (NIAID): 2,006 sponsored US clinical trials, 155 recruiting.

National Institute of Allergy and Infectious Diseases (NIAID) sponsors 2,006 registered US clinical trials on ClinicalTrials.gov, 155 of them currently recruiting, and 1,642 completed. 177 of these trials are in Phase 3-4 (later-stage) and 1,291 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is HIV Infections, with 195 trials.

Top-decile sponsor footprint

National Institute of Allergy and Infectious Diseases (NIAID) ranks in the top decile of sponsors by registered trial count (#5 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 68/100

1,642 of 1,802 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.1%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

2,006 total, page 3 of 41

RECRUITING

Type 1 Diabetes Extension Study

NCT02734277

RECRUITING

Natural History and Genetics of Food Allergy and Related Conditions

NCT02504853

RECRUITING Phase 1

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

NCT02140255

RECRUITING

Novel Genetic Disorders of the Immune System

NCT02257892

RECRUITING

Pathogenesis and Genetics of Disseminated or Refractory Coccidioidomycosis

NCT02190266

RECRUITING

PET Imaging and Lymph Node Assessment of IRIS in People With AIDS

NCT02147405

RECRUITING Phase 2

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

NCT02015013

RECRUITING

Natural History Study of GATA2 Deficiency and Related Disorders

NCT01905826

RECRUITING

Natural History of Individuals With Immune System Problems That Lead to Fungal Infections

NCT01386437

RECRUITING Phase 1

Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

NCT01306019

RECRUITING

Screening Volunteers for Clinical Trials

NCT01375530

RECRUITING

Admission and Management of Occupational or Other Exposures to Biodefense/Bioterrorism Agents or to Epidemic/Emerging Infectious Diseases

NCT01200953

RECRUITING

Screening for LID Clinical Studies Unit Healthy Volunteer Protocols

NCT01386424

RECRUITING

Training Protocol on the Natural History of Tuberculosis

NCT01212003

RECRUITING

Viral Infections in Healthy and Immunocompromised Hosts

NCT01306084

RECRUITING

Studies of Disorders With Increased Susceptibility to Fungal Infections

NCT01222741

RECRUITING

VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and Older

NCT01132859

RECRUITING Phase 1

A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

NCT00967785

RECRUITING

The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise

NCT01011712

RECRUITING

Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

NCT00867269

RECRUITING

Clinical and Immunologic Monitoring of Patients With Known or Suspected HIV Infection

NCT00789009

RECRUITING

Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System

NCT00794352

RECRUITING

Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

NCT00246857

RECRUITING

Detection and Characterization of Infections and Infection Susceptibility

NCT00404560

RECRUITING

Evaluation of Patients With Immune Function Abnormalities

NCT00128973

RECRUITING

A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression

NCT00091871

RECRUITING

Collection of Data and Samples From Healthy Donors for Use in Translational Research

NCT00090662

RECRUITING

Apheresis and Specimen Collection Procedures to Obtain Plasma, Peripheral Blood Mononuclear Cells (PBMCs) and Other Specimens for Research Studies

NCT00067054

RECRUITING

Natural History of Anthrax: a Study of Primary Infected, Recovered, and Exposed Individuals (SPoRE); and Evaluation of AVA-Vaccinated Recipients

NCT00050310

RECRUITING

Study of Factors Regulating Mast Cell Proliferation

NCT00044122

RECRUITING

Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naive HIV-1 Research Participants

NCT00039689

RECRUITING

Genetic Studies of Chronic Active Epstein-Barr Disease

NCT00032513

RECRUITING

Evaluation, Treatment, and Follow-up of Patients With Lyme Disease

NCT00028080

RECRUITING

Diagnosis and Treatment of Leishmania Infections

NCT00344188

RECRUITING

Leukapheresis to Obtain Plasma or Lymphocytes for Studies of HIV-infected Patients, Including Long-term Non-progressors

NCT00029445

RECRUITING

Molecular Basis of Human Phagocyte Interactions With Bacterial Pathogens

NCT00339287

RECRUITING

Study of Mycobacterial Infections

NCT00018044

RECRUITING

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

NCT00006150

RECRUITING Phase 4

Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis

NCT00004317

RECRUITING

Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection

NCT00001645

RECRUITING

Immune Regulation in Ulcerative Colitis or Crohn s Disease

NCT00001184

RECRUITING

Activation and Function of Eosinophils in Conditions With Blood or Tissue Eosinophilia

NCT00001406

RECRUITING

A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations

NCT00001539

RECRUITING

Genetic Analysis of Immune Disorders

NCT00001467

RECRUITING

Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes

NCT00001405

RECRUITING

Detection and Characterization of Host Defense Defects

NCT00001355

RECRUITING

Study of Autoimmune Lymphoproliferative Syndrome (ALPS)

NCT00001350

RECRUITING

Fungal Infection Susceptibility

NCT00001352

RECRUITING

Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in People Living With and Without HIV

NCT00001281

RECRUITING

Viral Load in Blood and Lymph Tissues in People Living With HIV

NCT00001316

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Phase Distribution

PhaseTrial count
Phase 1 858
Phase 2 433
Phase 3 123
Phase 4 54

What is open in the National Institute of Allergy and Infectious Diseases (NIAID) pipeline

155 recruiting of 2,006 indexed (8% open); 1,642 completed (82%).

Phase mix: 177 late (III/IV) vs 1,291 early (I/II) (early-phase heavy).

Top condition: HIV Infections (195 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

National Institute of Allergy and Infectious Diseases (NIAID): open-pipeline peers nationwide

Peers matched on 2,006 registered trials and 8% open enrollment, not the therapeutic-area sidebar.

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,5002,0002,500 5%10%15%20% Total trials Recruiting share National Institute of Allergy and Infectious Diseases (NIAID)Massachusetts General HospitalMemorial Sloan Kettering Cancer CenterPfizerStanford UniversityAlumisAndrei IagaruBioXcel TherapeuticsCorporal Michael J. Crescenz VA Medical Center
National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

National Institute of Allergy and Infectious Diseases (NIAID) sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 2,006 trials (± recruiting share)

Sponsors near 8% open enrollment (± trial volume)

What to do with this National Institute of Allergy and Infectious Diseases (NIAID) page

2,006 registered trials is a research-attention snapshot, not an endorsement of National Institute of Allergy and Infectious Diseases (NIAID) or any single study.

  • 155 of National Institute of Allergy and Infectious Diseases (NIAID)'s trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • HIV Infections is the condition National Institute of Allergy and Infectious Diseases (NIAID) studies most, compare against other sponsors active in the same condition before evaluating a specific study. See HIV Infections trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. National Institute of Allergy and Infectious Diseases (NIAID) pipeline card: 2,006 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.