Medtronic Cardiac Rhythm and Heart Failure

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Medtronic Cardiac Rhythm and Heart Failure sits in the top decile of US sponsors by registered trial count (#223 of 15,742 sponsors by registered trial count).

115 total trials 2 currently recruiting 100 completed top decile by trial count

Medtronic Cardiac Rhythm and Heart Failure: 115 sponsored US clinical trials, 2 recruiting.

Medtronic Cardiac Rhythm and Heart Failure sponsors 115 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 100 completed. 6 of these trials are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Heart Failure, with 10 trials.

Top-decile sponsor footprint

Medtronic Cardiac Rhythm and Heart Failure ranks in the top decile of sponsors by registered trial count (#223 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

100 of 109 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

115 total, page 1 of 3

RECRUITING NA

ELEVATE-HFpEF Clinical Study

NCT06678841

RECRUITING NA

Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction

NCT05839730

ACTIVE NOT RECRUITING

Cardiac Implantable Electronic Device (CIED) Research Study

NCT05061862

ACTIVE NOT RECRUITING

Destination Therapy Post Approval Study

NCT03681210

ACTIVE NOT RECRUITING

Characterizing Outcomes and Real-World Experience of Cardiac Physiologic Pacing (The CORE-CPP Study)

NCT06606288

ACTIVE NOT RECRUITING NA

DelIVery for Pulmonary Arterial Hypertension (PAH) & Continued Support Study

NCT01321073

COMPLETED

Crome/Cobalt Respiration Study

NCT06089694

COMPLETED

QT Changes as Detected From LINQ ECG During Antiarrhythmic Loading (LINQ QT)

NCT05488470

COMPLETED

TYRX™ Pocket Health Study

NCT05356546

COMPLETED NA

Conduction System Pacing Optimized Therapy

NCT04905290

COMPLETED NA

Lead EvaluAtion for Defibrillation and Reliability (LEADR) / Lead Evaluation for Defibrillation and Reliability in Left Bundle Branch Area Pacing (LEADR LBBAP)

NCT04863664

TERMINATED

DEFINE AFib (Atrial Fibrillation)

NCT04926857

COMPLETED

Reveal LINQ Respiration Clinical Study

NCT04506684

COMPLETED NA

Algorithm Using LINQ Sensors for Evaluation And Treatment of Heart Failure

NCT04452149

COMPLETED

Reveal LINQ for Chronic Obstructive Pulmonary Disease (COPD)

NCT04169529

COMPLETED NA

Accelerometer Sensing for Micra AV Study

NCT04245345

COMPLETED NA

Extravascular ICD Pivotal Study

NCT04060680

COMPLETED

SelectSecure 3830 Lead Imaging

NCT03941275

COMPLETED NA

Micra Atrial TRacking Using A Ventricular AccELerometer 2

NCT03752151

COMPLETED

Apogee, A HeartWare HVAD Destination Product Surveillance Registry (PSR) Platform

NCT03697980

COMPLETED NA

ECG Belt for CRT Response

NCT03504020

COMPLETED NA

Relationship Between LINQ™ Subcutaneous Impedance and Right-sided Hemodynamic Measurements

NCT03608826

COMPLETED

BlueSync Field Evaluation

NCT03518658

COMPLETED

Tachy Prediction Download Study

NCT03402126

COMPLETED

Imaging Study of Lead Implant for His Bundle Pacing

NCT03294317

COMPLETED NA

REmodeling the Left Ventricle With Atrial Modulated Pacing

NCT03210402

COMPLETED Phase 1

Micra Atrial Tracking Using a Ventricular Accelerometer Study

NCT03157297

COMPLETED NA

Attain Stability™ Quad Clinical Study

NCT03099655

COMPLETED

Magnetic Resonance Imaging of Human Biometrics

NCT02942667

COMPLETED NA

Pressure Variability Study

NCT02943941

COMPLETED

Reveal LINQ™ Heart Failure

NCT02758301

COMPLETED NA

Acute Study to Collect Electrical Signals From the Heart Using a Special Lead

NCT02772380

TERMINATED NA

Integrated Diagnostics Driven Diuretic and Chronic Medication Management for Heart Failure

NCT02698241

COMPLETED NA

Rate of Atrial Fibrillation Through 12 Months in Patients With Recent Ischemic Stroke of Presumed Known Origin

NCT02700945

COMPLETED

SEEQ™ Performance Study

NCT02484898

COMPLETED NA

Medtronic Reveal LINQ™ In-Office 2 (RIO 2) Study United States

NCT02395536

COMPLETED Phase 4

World-wide Randomized Antibiotic Envelope Infection Prevention Trial

NCT02277990

COMPLETED NA

HW006 LATERAL Thoracotomy

NCT02268942

COMPLETED NA

Cardiac Resynchronization Therapy Efficacy Enhancements

NCT02222818

COMPLETED NA

AdaptResponse Clinical Trial

NCT02205359

COMPLETED

Reveal LINQ Registry

NCT02746471

COMPLETED NA

Confirmatory Clinical Trial of the Evera MRI System for Conditionally-safe MRI Access

NCT02117414

COMPLETED NA

Feasibility Study of Remote Support for Implantable Pulse Generator (IPG)/Implantable Cardioverter Defibrillator (ICD) Implant

NCT01809652

COMPLETED NA

Micra Transcatheter Pacing Study

NCT02004873

COMPLETED NA

A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL)

NCT01966458

COMPLETED NA

Sensor Optimization of Cardiac Resynchronization Therapy Response

NCT01832493

COMPLETED

Post- Approval Study on Patients Who Received a HeartWare HVAD® During IDE Trials

NCT01832610

COMPLETED NA

Attain Performa(TM) Quadripolar Lead Study

NCT01751022

TERMINATED NA

MIRACLE EF Clinical Study

NCT01735916

COMPLETED NA

REVEAL AF: Incidence of AF in High Risk Patients

NCT01727297

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What is open in the Medtronic Cardiac Rhythm and Heart Failure pipeline

2 recruiting of 115 indexed (2% open); 100 completed (87%).

Phase mix: 6 late (III/IV) vs 5 early (I/II) (balanced across stages).

Top condition: Heart Failure (10 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Medtronic Cardiac Rhythm and Heart Failure: open-pipeline peers nationwide

Peers matched on 115 registered trials and 2% open enrollment, not the therapeutic-area sidebar.

Medtronic Cardiac Rhythm and Heart Failure sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300 0%5%10%15%20%25% Total trials Recruiting share Medtronic Cardiac Rhythm and Heart FailureMedstar Health Research InstituteZimmer BiometRockefeller UniversityState University of New York - Upstate Medical UniversityEisaiBausch & Lomb IncorporatedLexicon PharmaceuticalsAlcon Research
Medtronic Cardiac Rhythm and Heart Failure sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Medtronic Cardiac Rhythm and Heart Failure sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 115 trials (± recruiting share)

Sponsors near 2% open enrollment (± trial volume)

What to do with this Medtronic Cardiac Rhythm and Heart Failure page

115 registered trials is a research-attention snapshot, not an endorsement of Medtronic Cardiac Rhythm and Heart Failure or any single study.

  • 2 of Medtronic Cardiac Rhythm and Heart Failure's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Heart Failure is the condition Medtronic Cardiac Rhythm and Heart Failure studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Heart Failure trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Medtronic Cardiac Rhythm and Heart Failure pipeline card: 115 registered trials from official public datasets.Report a data error.