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Cardiac Resynchronization Therapy Efficacy Enhancements
NCT02222818 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to demonstrate that the amount of effective CRT (Cardiac Resynchronization Therapy) pacing during AF (atrial fibrillation) when CAFRPlus (Conducted AF Response Plus) is applied is not inferior to the amount of effective CRT pacing during AF when CAFR (Conducted AF Response) is applied.
Conditions Studied
Interventions
- DEVICE Conducted AF Response (CAFR)
- DEVICE Conducted AF Response Plus (CAFRPlus)
Study Locations (19)
Other
- Magyar Honvédség Honvédkorház — Budapest
- Policlinico Universitario Agostino Gemelli — Roma
- Azienda Ospedaliera Bolognini Seriate - Ospedale Bolognini — Seriate
- Azienda Ospedaliera Cardinale Panico — Tricase
- Prince Sultan Cardiac Center — Riyadh
- Vychodoslovensky ustav srdcovych a cievnych chorob, a.s. — Košice
- Mediclinic Panorama — Cape Town
- Liverpool Heart and Chest Hospital NHS Foundation Trust — Liverpool
- he Newcastle upon Tyne Hospitals NHS Foundation Trust - Freeman Hospital — Newcastle upon Tyne
Minnesota
- North Memorial Heart and Vascular — Minneapolis
- CentraCare — Saint Cloud
Florida
- Cardiac Arrythmia Services — Boca Raton
Iowa
- Iowa Heart Center — West Des Moines
North Carolina
- North Carolina Heart and Vascular — Raleigh
Ohio
- Mount Carmel — Columbus
Oklahoma
- Oklahoma Heart — Oklahoma City
Pennsylvania
- Berks Cardiology — Reading
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 71 participants |
| Start Date | 2014-10 |
| Est. Completion | 2016-01 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02222818
The ClinicalTrials.gov registry entry for NCT02222818 describes a study currently listed as completed. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 71 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Medtronic Cardiac Rhythm and Heart Failure, which has 56 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Atrial Fibrillation appearing as the primary indexed condition, and to 2 interventions — of which Conducted AF Response (CAFR) is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT02222818 reports 19 study locations spanning 10 distinct geographic areas — top geographies include Other, Minnesota, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT02222818 about?
NCT02222818 is a clinical study titled "Cardiac Resynchronization Therapy Efficacy Enhancements". The purpose of this study is to demonstrate that the amount of effective CRT (Cardiac Resynchronization Therapy) pacing during AF (atrial fibrillation) when CAFRPlus (Conducted AF Response Plus) is applied is not inferior to the amount of effective CRT pacing during AF when CAFR (Conducted AF Respon...
What is the current status of trial NCT02222818?
This trial is currently completed. It is a NA study. The enrollment target is 71 participants. The study started on 2014-10. Estimated completion is 2016-01.
What conditions does trial NCT02222818 study?
This clinical trial studies the following conditions: Atrial Fibrillation. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT02222818?
The interventions under investigation include: Conducted AF Response (CAFR) (DEVICE), Conducted AF Response Plus (CAFRPlus) (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT02222818?
This trial is sponsored by Medtronic Cardiac Rhythm and Heart Failure, which has 56 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT02222818 being conducted?
This trial has 19 study locations across Florida, Iowa, Minnesota, North Carolina, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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