Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05839730 · ClinicalTrials.gov registry record · NA
Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction
A NA study of Heart Failure With Preserved Ejection Fraction and Concentric Hypertrophy, sponsored by Medtronic Cardiac Rhythm and Heart Failure.
- Recruiting
- Registry status
- NA
- Development phase
- 105
- Enrollment target
- 9
- Study locations
NCT05839730 is a NA study of Heart Failure With Preserved Ejection Fraction and Concentric Hypertrophy that is actively recruiting participants, run by Medtronic Cardiac Rhythm and Heart Failure. The registered enrollment target is 105 participants, below the 2,286-participant average among 42 other Heart Failure With Preserved Ejection Fraction trials with a reported enrollment target (95% lower). The trial reports 9 study locations across 7 states.
The verdict
NCT05839730, a NA study of Heart Failure With Preserved Ejection Fraction and Concentric Hypertrophy, is actively recruiting participants, sponsored by Medtronic Cardiac Rhythm and Heart Failure.
- RECRUITING
- Registry status
- NA
- Development phase
- 105 participants
- Enrollment target
- 9
- Study locations
Study Summary
FIRE-HFpEF is a multi-center, prospective, randomized, single-blinded, clinical feasibility study. This study will enroll up to 105 subjects with heart failure with preserved ejection fraction in the United States. Data will be collected to evaluate whether pacing therapies can lead to improvements in exercise capacity and health status of subjects.
Conditions Studied
Interventions
- DEVICE Pacemaker PLR + TRT ON
- DEVICE Pacemaker non-pacing mode or an exertional rate-adaptive pacing mode with no planned pacing at rest.
Study Locations (9)
Illinois
- Prairie Education and Research Cooperative-St. Elizabeth's - O'Fallon
- Prairie Education and Research Cooperative-St. John's - Springfield
Texas
- Dallas VA Medical Center - Dallas
- Houston Methodist Research Institute - Houston
Florida
- NCH Heart Institute - Naples
Kansas
- University of Kansas Medical Center - Kansas City
North Carolina
- Duke University - Durham
Oklahoma
- Oklahoma Heart Hospital - Oklahoma City
Vermont
- The University of Vermont Medical Center - Burlington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 105 participants |
| Start Date | 2024-09-11 |
| Est. Completion | 2027-07 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05839730
The ClinicalTrials.gov registry entry for NCT05839730 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,286-participant average among 42 other Heart Failure With Preserved Ejection Fraction trials with a reported enrollment target (95% lower). The listed sponsor is Medtronic Cardiac Rhythm and Heart Failure, which has 115 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Heart Failure With Preserved Ejection Fraction appearing as the primary indexed condition, and to 2 interventions - of which Pacemaker PLR + TRT ON is the first listed.
NCT05839730 reports 9 study locations spanning 7 distinct geographic areas - top geographies include Illinois, Texas, Florida.
Frequently Asked Questions
What is clinical trial NCT05839730 about?
NCT05839730 is a clinical study titled "Fast Induced Remodeling in Heart Failure With Preserved Ejection Fraction". FIRE-HFpEF is a multi-center, prospective, randomized, single-blinded, clinical feasibility study. This study will enroll up to 105 subjects with heart failure with preserved ejection fraction in the United States. Data will be collected to evaluate whether pacing therapies can lead to improvements ...
What is the current status of trial NCT05839730?
This trial is currently recruiting. It is a NA study. The enrollment target is 105 participants. The study started on 2024-09-11. Estimated completion is 2027-07.
What conditions does trial NCT05839730 study?
This clinical trial studies the following conditions: Heart Failure With Preserved Ejection Fraction, Concentric Hypertrophy.
What interventions are being tested in trial NCT05839730?
The interventions under investigation include: Pacemaker PLR + TRT ON (DEVICE), Pacemaker non-pacing mode or an exertional rate-adaptive pacing mode with no planned pacing at rest. (DEVICE).
Who is sponsoring clinical trial NCT05839730?
This trial is sponsored by Medtronic Cardiac Rhythm and Heart Failure, which has 115 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05839730 being conducted?
This trial has 9 study locations across Florida, Illinois, Kansas, North Carolina, Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Heart Failure With Preserved Ejection Fraction
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)
RECRUITING · NA
-
Ketogenic Diet vs Mixed Diet in Patients With Heart Failure
RECRUITING · NA
-
Pilot Study Lp299v Supplementation in Chronic Heart Failure
RECRUITING · NA
-
Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction
RECRUITING · NA
-
Transitions of Care Clinic (TOCC)
RECRUITING · NA
-
Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF
RECRUITING · NA
Explore more on PlainTrial
Heart Failure With Preserved Ejection Fraction
All registered trials for this condition
Concentric Hypertrophy
All registered trials for this condition
Florida
All trials with a study site in Florida
Recruiting now
Find trials open to new participants near you
Rankings
Top sponsors, conditions, and phases
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.