Medtronic Cardiac Rhythm and Heart Failure

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, Medtronic Cardiac Rhythm and Heart Failure sits in the top decile of US sponsors by registered trial count (#223 of 15,742 sponsors by registered trial count).

115 total trials 2 currently recruiting 100 completed top decile by trial count

Medtronic Cardiac Rhythm and Heart Failure: 115 sponsored US clinical trials, 2 recruiting.

Medtronic Cardiac Rhythm and Heart Failure sponsors 115 registered US clinical trials on ClinicalTrials.gov, 2 of them currently recruiting, and 100 completed. 6 of these trials are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Heart Failure, with 10 trials.

Top-decile sponsor footprint

Medtronic Cardiac Rhythm and Heart Failure ranks in the top decile of sponsors by registered trial count (#223 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 69/100

100 of 109 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

115 total, page 2 of 3

COMPLETED

REducing 30-day ADMIssions in posT-discharge Subjects (READMIT)

NCT01574144

COMPLETED

Cutaneous Heart Sounds Data Collection During Cardiac Resynchronization Therapy (CRT) Optimization Study

NCT01609985

COMPLETED NA

Diagnostic Device Risk Management of Atrial Fibrillation and Heart Failure

NCT01486316

COMPLETED Phase 1

Acute Carotid Sinus Endovascular Stimulation II Study

NCT01458483

COMPLETED Phase 2

Feasibility of an Integrated Patient Care (IPC) System Using Daily Filling Pressures

NCT01370564

COMPLETED Phase 2

Post-Myocardial Infarction Remodeling Prevention Therapy

NCT01213251

COMPLETED NA

The HeartWare™ Ventricular Assist System as Destination Therapy of Advanced Heart Failure: the ENDURANCE Trial

NCT01166347

COMPLETED

Reveal In-Office Implants

NCT01168427

COMPLETED NA

Advisa MRI Clinical Study

NCT01110915

COMPLETED Phase 2

Determining the Feasibility of Spinal Cord Neuromodulation for the Treatment of Chronic Heart Failure

NCT01112579

COMPLETED NA

Feasibility Study of an Integrated Diagnostic System to Manage Heart Failure

NCT01045343

COMPLETED

Attain Success Clinical Trial

NCT00990964

COMPLETED NA

Adaptive Cardiac Resynchronization Therapy Study

NCT00980057

COMPLETED

Extension Phase of the Chronicle® Offers Management to Patients With Advanced Signs & Symptoms of Heart Failure Study

NCT00991120

COMPLETED NA

Safety and Clinical Performance of the Protecta ICD and CRT-D

NCT00982397

COMPLETED NA

Optimize RV Follow-up Selective Site Pacing Clinical Trial

NCT00949715

COMPLETED

Attain StarFix® 4195 Lead Extraction Study

NCT00893386

COMPLETED Phase 4

Study of Continuous Cardiac Monitoring to Assess Atrial Fibrillation After Cryptogenic Stroke

NCT00924638

COMPLETED

Medtronic Shock-Less Study on Physician Utilization of Shock Reduction Programming

NCT00856349

COMPLETED NA

Continued Access Protocol

NCT00889681

COMPLETED NA

Model 4396 Left Ventricular (LV) Lead Study

NCT00853593

COMPLETED Phase 4

OptiVol® Care Pathway

NCT00847288

COMPLETED NA

Evaluation of the HeartWare Left Ventricular Assist Device for the Treatment of Advanced Heart Failure

NCT00751972

TERMINATED

ST Segment Detection Study

NCT00930969

TERMINATED NA

Evaluation of Cardiac Compass With OptiVol in the Early Detection of Decompensation Events for Heart Failure

NCT00510198

COMPLETED Phase 3

Tailored Treatment of Permanent Atrial Fibrillation

NCT00514735

COMPLETED NA

EMRI SureScan™ Clinical Study

NCT00433654

COMPLETED NA

Attain Model 4196 Left Ventricular (LV) Lead

NCT00271544

TERMINATED NA

Optimize RV Selective Site Pacing Clinical Trial

NCT00422669

COMPLETED Phase 4

CryoCath Freezor CryoAblation Catheter System (CRYOFACTS)

NCT00621621

COMPLETED NA

CONNECT Study - Clinical Evaluation Of Remote NotificatioN to rEduCe Time to Clinical Decision

NCT00402246

COMPLETED Phase 3

A Clinical Study of the Arctic Front Cryoablation Balloon for the Treatment of Paroxysmal Atrial Fibrillation

NCT00523978

COMPLETED NA

D2-EPG Study: Evaluation of New Sensing Circuitry and Capture Management

NCT00328705

COMPLETED NA

Reducing Decompensation Events Utilizing Intracardiac Pressures in Patients With Chronic Heart Failure (HF) (REDUCEhf)

NCT00354159

COMPLETED NA

Clinical Investigation of the Medtronic Concerto™ Device

NCT00268320

TERMINATED

OMNI Study--Assessing Therapies in Medtronic Pacemaker, Defibrillator, and Cardiac Resynchronization Therapy Devices.

NCT00277524

COMPLETED

IMPROVE HF: Registry to Improve the Use of Evidence-Based Heart Failure Therapies in the Outpatient Setting

NCT00303979

COMPLETED NA

Left Ventricular Capture Management (LVCM) Software Download Clinical Trial

NCT00268281

TERMINATED NA

Managed Ventricular Pacing ("MVP") Trial

NCT00281099

COMPLETED NA

REsynchronization reVErses Remodeling in Systolic Left vEntricular Dysfunction (REVERSE)

NCT00271154

COMPLETED NA

Attain StarFix™ Model 4195 Left Ventricular Lead

NCT00269230

COMPLETED

PARTNERS HF: Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure

NCT00279955

COMPLETED

Ensure Cardiac Resynchronization Therapy Study

NCT00291564

COMPLETED NA

PREFER (Pacemaker Remote Follow-Up Evaluation and Review)

NCT00294645

COMPLETED NA

Clinical Investigation of the Medtronic EnTrust™ Implantable Cardioverter Defibrillator (ICD), Model D153ATG

NCT00273195

COMPLETED

PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy

NCT00253357

COMPLETED NA

CAPTURE - Complete Automatic Pacing Threshold Utilization Recorded by EnPulse

NCT00275769

TERMINATED

P3: Pacemaker Patient Profiling Study

NCT00294060

COMPLETED

INSIGHTS ICD Registry

NCT00279968

COMPLETED NA

Reducing Episodes by Septal Pacing Efficacy Confirmation Trial (RESPECT)

NCT00289289

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What is open in the Medtronic Cardiac Rhythm and Heart Failure pipeline

2 recruiting of 115 indexed (2% open); 100 completed (87%).

Phase mix: 6 late (III/IV) vs 5 early (I/II) (balanced across stages).

Top condition: Heart Failure (10 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Medtronic Cardiac Rhythm and Heart Failure: open-pipeline peers nationwide

Peers matched on 115 registered trials and 2% open enrollment, not the therapeutic-area sidebar.

Medtronic Cardiac Rhythm and Heart Failure sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300 0%5%10%15%20%25% Total trials Recruiting share Medtronic Cardiac Rhythm and Heart FailureMedstar Health Research InstituteZimmer BiometRockefeller UniversityState University of New York - Upstate Medical UniversityEisaiBausch & Lomb IncorporatedLexicon PharmaceuticalsAlcon Research
Medtronic Cardiac Rhythm and Heart Failure sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Medtronic Cardiac Rhythm and Heart Failure sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 115 trials (± recruiting share)

Sponsors near 2% open enrollment (± trial volume)

What to do with this Medtronic Cardiac Rhythm and Heart Failure page

115 registered trials is a research-attention snapshot, not an endorsement of Medtronic Cardiac Rhythm and Heart Failure or any single study.

  • 2 of Medtronic Cardiac Rhythm and Heart Failure's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Heart Failure is the condition Medtronic Cardiac Rhythm and Heart Failure studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Heart Failure trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Medtronic Cardiac Rhythm and Heart Failure pipeline card: 115 registered trials from official public datasets.Report a data error.