M.D. Anderson Cancer Center

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, M.D. Anderson Cancer Center sits in the top decile of US sponsors by registered trial count (#3 of 15,751 sponsors by registered trial count).

2,692 total trials 549 currently recruiting 1201 completed early-phase tilt top decile by trial count

M.D. Anderson Cancer Center: 2,692 sponsored US clinical trials, 549 recruiting.

M.D. Anderson Cancer Center sponsors 2,692 registered US clinical trials on ClinicalTrials.gov, 549 of them currently recruiting, and 1,201 completed. 124 of these trials are in Phase 3-4 (later-stage) and 1,719 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hematopoietic and Lymphoid Cell Neoplasm, with 44 trials.

Top-decile sponsor footprint

M.D. Anderson Cancer Center ranks in the top decile of sponsors by registered trial count (#3 of 15,751 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Open and recent trials

2,692 total, page 34 of 54

COMPLETED Phase 2

Minocycline Study in Pancreatic Cancer Patients

NCT01693523

TERMINATED Phase 1

Intrathecal Rituximab in Lymphoid Malignancies Involving Central Nervous System

NCT01596127

COMPLETED Phase 2

Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT)

NCT01490723

COMPLETED Phase 2

Dexamethasone Dyspnea Study

NCT01670097

COMPLETED Early Phase 1

Methotrexate Infusion Into the Fourth Ventricle in Children With Malignant Fourth Ventricular Brain Tumors: A Pilot Study

NCT01737671

COMPLETED Phase 1

Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer

NCT01596140

COMPLETED Phase 1

Pilot Study to Determine Effects of the Btk Inhibitor PCI-32765 on Leukemia Cell Kinetics and Trafficking, Using Heavy Water Labeling in Subjects With CLL and SLL

NCT01752426

COMPLETED Phase 1

Infusion of Allogeneic Umbilical Cord Blood-Derived Cluster of Differentiation Antigen 19 (CD19)-Specific T Cells

NCT01362452

COMPLETED Phase 2

Preventing Sexual Dysfunction With Aromatase Inhibitors

NCT01603303

COMPLETED Phase 2

Ixazomib Citrate and Lenalidomide After Stem Cell Transplant in Treating Patients With Newly Diagnosed Multiple Myeloma

NCT01718743

COMPLETED Phase 2

Nivolumab and Ipilimumab in Treating Patients With Metastatic Uveal Melanoma

NCT01585194

COMPLETED Phase 2

Surgery and/or Radiation Therapy or Standard Therapy and/or Clinical Observation in Treating Patients With Previously Treated Stage IV Non-small Cell Lung Cancer

NCT01725165

TERMINATED Phase 1

Allogeneic Stem Cell Transplant for CLL

NCT01629511

TERMINATED Phase 1

Tosedostat and Cytarabine or Azacitidine in Treating Older Participants With Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

NCT01636609

TERMINATED

Gene Expression in Hyperparathyroidism

NCT03044600

COMPLETED Phase 2

Decitabine Versus Azacitidine in Myelodysplastic Syndrome Patients With Low and Intermediate-1 Risk

NCT01720225

COMPLETED Phase 2

Abraxane in CIMP-High Colorectal and Small Bowel Adenocarcinomas

NCT01730586

COMPLETED

Using Multimedia Approaches to Communicate Probabilities in Patient Decision Aids for Low-Literacy Populations: Randomized Trial

NCT02151032

COMPLETED NA

Magnetic Resonance Imaging of Gynecologic Malignancies Involving the Vagina

NCT01703195

TERMINATED Phase 2

TKI 258 in Von Hippel-Lindau Syndrome (VHL)

NCT01266070

TERMINATED Phase 1

Doxycycline, Temozolomide and Ipilimumab in Melanoma

NCT01590082

COMPLETED Phase 1

Romidepsin, Ifosfamide, Carboplatin, and Etoposide in Treating Participants With Relapsed or Refractory Peripheral T-Cell Lymphoma

NCT01590732

COMPLETED Phase 1

CMC-544 and Allogeneic Transplantation for CD22 Positive-Lymphoid Malignancies

NCT01664910

COMPLETED NA

Brief Guided Relaxation for Women Undergoing Stereotactic Breast Biopsy

NCT03023215

COMPLETED Phase 1

Gemcitabine Hydrochloride, Clofarabine, and Busulfan Before Donor Stem Cell Transplant in Treating Patients With Refractory B-Cell or T-Cell Non-Hodgkin Lymphoma or Hodgkin Lymphoma

NCT01701986

COMPLETED Phase 2

Pazopanib Versus Temsirolimus in Poor-Risk Clear-Cell Renal Cell Carcinoma (RCC)

NCT01392183

COMPLETED NA

Magnetic Resonance Imaging (MRI) Brachytherapy Applicator Study

NCT01706705

COMPLETED

Adaptation of the American Cancer Society (ACS) Early Detection of Prostate Cancer Patient Decision Aid for Spanish Speaking Men

NCT01447186

COMPLETED NA

REcovery of Left Ventricular Dysfunction in CAncer Patients (RECAP Trial)

NCT02543294

COMPLETED

The Effect of Dexmedetomidine of the Immune System

NCT01692210

COMPLETED Phase 2

An Open-Label Phase II Study of the Combination of GSK2118436 and GSK1120212 in Patients With Metastatic Melanoma Which is Refractory or Resistant to BRAF Inhibitor

NCT01619774

TERMINATED Phase 2

Exemestane-RAD001-Metformin

NCT01627067

COMPLETED Phase 1

Azacitidine (AZA) in Minimal Residual Disease (MRD) Chronic Myeloid Leukemia (CML)

NCT01460498

COMPLETED NA

R-21 Colorectal Cancer Screening (CRCS) Pilot Trial

NCT01492049

COMPLETED NA

A Prospective Study Using Implanted Fiducial Markers to Assess Treatment Accuracy and Esophageal Toxicity in Spinal Stereotactic Body Radiation Therapy

NCT01624220

COMPLETED Phase 2

Neoadjuvant Study of Sequential Eribulin Followed by FAC Compared to Sequential Paclitaxel Followed by FEC in Early Stage Breast Cancer Not Overexpressing HER-2

NCT01593020

TERMINATED Phase 2

Stereotactic Body Radiotherapy (SBRT) Versus Stereotactic Body Proton Therapy (SBPT)

NCT01511081

TERMINATED Phase 2

A Study of the HSP90 Inhibitor AUY922

NCT01485536

TERMINATED NA

Lacosamide in Preventing Seizures in Participants With Malignant Glioma

NCT01432171

COMPLETED

Prospective Study to Determine Impact of Early Palliative Care Consult on Quality of Life (QOL), Cancer Related Symptoms In Advanced Lung Cancer Patients: Thoracic Pilot Project

NCT02459002

COMPLETED

Genomic Profiling Assay in Phase I

NCT02437617

COMPLETED Phase 1

Cord Blood Fucosylation to Enhance Homing and Engraftment in Patients With Hematologic Malignancies

NCT01471067

COMPLETED Phase 1

Cabazitaxel With or Without Carboplatin in Treating Patients With Previously Treated Metastatic Castration-Resistant Prostate Cancer

NCT01505868

COMPLETED Phase 1

Study of Vemurafenib, Carboplatin, and Paclitaxel

NCT01636622

COMPLETED Phase 1

Study to Assess Safety, Tolerability and Preliminary Efficacy of BKM120, PI3K Kinase Inhibitor, With Advanced Leukemias

NCT01396499

COMPLETED

A Mixed-Methods Approach to Understanding Factors Associated With Cervical Cancer Screening Utilization Among Low-Income, HIV-Positive Women

NCT01605656

COMPLETED Phase 1

Imaging Study Compare 4DCT Image

NCT01626001

COMPLETED

Social Determinants and Smoking Cessation

NCT01310842

COMPLETED Phase 2

Minocycline Study in Non Small Cell Lung Cancer (NSCLC) Patients for Chemoradiation Therapy

NCT01636934

TERMINATED Phase 1

Phase I/II Bevacizumab Versus Bevacizumab Plus TPI 287 for Recurrent Glioblastoma

NCT01582152

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Phase Distribution

PhaseTrial count
Phase 1 748
Phase 2 971
Phase 3 96
Phase 4 28

What is open in the M.D. Anderson Cancer Center pipeline

549 recruiting of 2,692 indexed (20% open); 1,201 completed (45%).

Phase mix: 124 late (III/IV) vs 1,719 early (I/II) (early-phase heavy).

Top condition: Hematopoietic and Lymphoid Cell Neoplasm (44 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.