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NCT01693523 · ClinicalTrials.gov registry record · Phase 2

Minocycline Study in Pancreatic Cancer Patients

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Completed
Registry status
Phase 2
Development phase
80
Enrollment target

NCT01693523: Completed Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT01693523 is a Phase 2 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 80 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

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The verdict

NCT01693523, a Phase 2 study, has completed, sponsored by M.D. Anderson Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
80 participants
Enrollment target

Study Summary

The goal of this clinical research study is to learn if minocycline can reduce the side effects of chemotherapy in patients with pancreatic cancer. In this study, minocycline will be compared to a placebo. Minocycline is an antibiotic that may help to reduce side effects of chemotherapy. A placebo is not a drug. It looks like the study drug, but it is not designed to treat any disease or illness. It is designed to be compared with a study drug to learn if the study drug has any real effect.

Primary Outcome

Each item is rated on a 0 to 10 scale with 0 = symptom not present or no interference and 10 meaning the symptom severity is as bad as can be imagine or complete interference using the MD Anderson Symptom Inventory (MDASI). It is a measure of symptom burden, which includes symptom severity and how they interfere with daily functioning. For this study, the sub scale is the average of the 5 pre-selected items namely fatigue, pain, disturbed sleep, lack of appetite and drowsiness. This subscale ran

Interventions

  • OTHER Placebo
  • BEHAVIORAL Questionnaires
  • DRUG Minocycline

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2013-01-28
Est. Completion 2018-09-19
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

What the finished NCT01693523 record still lists

NCT01693523 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT01693523 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01693523 about?

NCT01693523 is a clinical study titled "Minocycline Study in Pancreatic Cancer Patients". The goal of this clinical research study is to learn if minocycline can reduce the side effects of chemotherapy in patients with pancreatic cancer. In this study, minocycline will be compared to a placebo. Minocycline is an antibiotic that may help to reduce side effects of chemotherapy. A placebo...

What is the current status of trial NCT01693523?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2013-01-28. Estimated completion is 2018-09-19.

What interventions are being tested in trial NCT01693523?

The interventions under investigation include: Placebo (OTHER), Questionnaires (BEHAVIORAL), Minocycline (DRUG).

Who is sponsoring clinical trial NCT01693523?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01693523's enrollment target sits among peer trials

80 842nd of 2000 higher than 1,117 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01693523, the US trial registry maintained by the National Library of Medicine. NCT01693523 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.